Localized Cutaneous Argyria at the Site of a Prior Melanoma Excision Confirmed by Scanning Electron Microscopy With Energy Dispersive X-ray Analysis.

Autor: McTighe SP; Dermatologist, Martin Army Community Hospital, Fort Moore, GA., Taylor EA; Dermatologist, Andrew Rader U.S. Army Health Clinic, Arlington, VA., Allbritton J; Dermatopathologist/Dermatologist, The Joint Pathology Center, Silver Spring, MD; and., Lewin-Smith MR; Dermatopathologist/Dermatologist, The Joint Pathology Center, Silver Spring, MD; and.; Senior Environmental Pathologist, The Joint Pathology Center, Silver Spring, MD.
Jazyk: angličtina
Zdroj: The American Journal of dermatopathology [Am J Dermatopathol] 2024 Mar 01; Vol. 46 (3), pp. 155-158. Date of Electronic Publication: 2023 Dec 26.
DOI: 10.1097/DAD.0000000000002610
Abstrakt: Abstract: Localized cutaneous argyria is a rare condition caused by the accumulation of silver particles in the skin, leading to blue-gray discoloration. Argyria may mimic melanoma and lead to misdiagnosis. We present a patient with a history of melanoma that developed a blue-gray nodule at a prior melanoma graft. The diagnosis was confirmed using scanning electron microscopy and energy dispersive x-ray analysis. These techniques differentiate argyria from melanoma and can be performed on formalin-fixed, paraffin-embedded, tissue sections. Health care providers should be alert that argyria may mimic recurrent melanoma in patients unaware of silver exposure.
Competing Interests: The authors declare no conflicts of interest.
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Databáze: MEDLINE