AFM 1 exposure in male balb/c mice and intervention strategies against its immuno-physiological toxicity using clay mineral and lactic acid bacteria alone or in combination.
Autor: | Aloui A; Laboratory of Genetic, Biodiversity and Bio-resources Valorisation, University of Monastir, Monastir, Tunisia.; Montpellier University, QUALISUD, UMR 95, Montpellier cedex 5, France., Ben Salah-Abbès J; Laboratory of Genetic, Biodiversity and Bio-resources Valorisation, University of Monastir, Monastir, Tunisia., Belgacem H; Laboratory of Genetic, Biodiversity and Bio-resources Valorisation, University of Monastir, Monastir, Tunisia., Dhif H; Laboratory of Genetic, Biodiversity and Bio-resources Valorisation, University of Monastir, Monastir, Tunisia., Zinedine A; BIOMARE Laboratory, Applied Microbiology and Biotechnology, Chouaib Doukkali University, El Jadida, Morocco., Riba A; Laboratoire de Biologie des Systèmes Microbiens (LBSM), Ecole Normale Supérieure de Kouba, Algiers, Algeria., Meile JC; CIRAD, UMR Qualisud, Montpellier, France.; Qualisud, Université de Montpellier, Avignon Université, CIRAD, Institut Agro, IRD, Université de La Réunion, Montpellier, France., Durande N; Qualisud, Université de Montpellier, Avignon Université, CIRAD, Institut Agro, IRD, Université de La Réunion, Montpellier, France., Brabet C; CIRAD, UMR Qualisud, Montpellier, France.; Qualisud, Université de Montpellier, Avignon Université, CIRAD, Institut Agro, IRD, Université de La Réunion, Montpellier, France., Abbès S; Laboratory of Genetic, Biodiversity and Bio-resources Valorisation, University of Monastir, Monastir, Tunisia. |
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Jazyk: | angličtina |
Zdroj: | Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2024 Apr; Vol. 46 (2), pp. 199-211. Date of Electronic Publication: 2024 Jan 11. |
DOI: | 10.1080/08923973.2023.2300299 |
Abstrakt: | Context: Aflatoxins are the most harmful mycotoxins that cause human and animal health concerns. Aflatoxin M Objectives: This study aimed to investigate, in vivo , the ability of lactic acid bacteria ( lactobacillus rhamnosus GAF01, LR) and clay mineral (bentonite, BT) mixture to mitigate/reduce AFM Materials and Methods: The in vivo study was conducted using male Balb/c mice that treated, orally, by AFM Results: The results showed that AFM Conclusion: In summary, the LR and/or BT was able to reduce the biochemical, histopathological and immunological damages induced by AFM |
Databáze: | MEDLINE |
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