Risk Factors for Serogroup B Meningococcal Disease Among College Students.
Autor: | Weil LM; Epidemic Intelligence Service Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Crowe SJ; Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Rubis AB; Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Soeters HM; Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Meyer SA; Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., Hariri S; Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA., McNamara LA; Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. |
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Jazyk: | angličtina |
Zdroj: | Open forum infectious diseases [Open Forum Infect Dis] 2023 Dec 02; Vol. 10 (12), pp. ofad607. Date of Electronic Publication: 2023 Dec 02 (Print Publication: 2023). |
DOI: | 10.1093/ofid/ofad607 |
Abstrakt: | Background: College students are at increased risk for invasive meningococcal disease, but which students are most at risk is unclear. Methods: US meningococcal disease cases in persons aged 18-24 years during 2014-2017 were included. Patients were classified as undergraduate students or other persons. Incidence in different student and non-student populations was compared. Results: During 2014-2017, 229 meningococcal disease cases were reported in persons aged 18-24 years; 120 were in undergraduate students. Serogroup B accounted for 74% of cases in students. Serogroup B disease incidence was 4-fold higher in undergraduate students, 11.8-fold higher among first-year undergraduate students, and 8.6-fold higher among residence hall residents versus non-undergraduates. During outbreaks, students affiliated with Greek life had a 9.8-fold higher risk of disease compared to other students. A significantly higher party school ranking was observed for schools with sporadic or outbreak cases when compared to schools with no cases. Conclusions: The findings of increased disease risk among first-year students and those living on campus or affiliated with Greek life can inform shared clinical decision-making for serogroup B vaccines to prevent this rare but serious disease. These data also can inform school serogroup B vaccination policies and outbreak response measures. Competing Interests: Potential conflicts of interest. The authors: No reported conflicts of interest. (Published by Oxford University Press on behalf of Infectious Diseases Society of America 2023.) |
Databáze: | MEDLINE |
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