Genetic characterization of parvoviruses identified in stray cats in Nigeria.

Autor: Oluwayelu DO; Department of Veterinary Microbiology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: do.oluwayelu@ui.edu.ng., Desario C; Department of Veterinary Medicine, University of Bari, Valenzano, Italy., Babalola ET; Department of Veterinary Microbiology and Parasitology, College of Veterinary Medicine, Federal University of Agriculture, Abeokuta, Nigeria., Pratelli A; Department of Veterinary Medicine, University of Bari, Valenzano, Italy., Daodu OB; Department of Veterinary Microbiology, Faculty of Veterinary Medicine, University of Ilorin, Ilorin, Nigeria., Elia G; Department of Veterinary Medicine, University of Bari, Valenzano, Italy., Odemuyiwa SO; Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, United States., Buonavoglia C; Department of Veterinary Medicine, University of Bari, Valenzano, Italy., Decaro N; Department of Veterinary Medicine, University of Bari, Valenzano, Italy., Diakoudi G; Department of Veterinary Medicine, University of Bari, Valenzano, Italy.
Jazyk: angličtina
Zdroj: Acta tropica [Acta Trop] 2024 Feb; Vol. 250, pp. 107108. Date of Electronic Publication: 2023 Dec 23.
DOI: 10.1016/j.actatropica.2023.107108
Abstrakt: Parvoviruses are a major cause of haemorrhagic gastroenteritis, leukopenia and high mortality in cats and dogs. In this study, the presence and genetic characteristics of parvoviruses circulating among cats in Nigeria are reported. Faecal samples of stray cats from live animal markets in southwestern (Oyo and Osun States) and north-central (Kwara State) Nigeria were screened for the presence of parvoviral DNA using a qPCR. Positive samples were further characterized using a qPCR based on minor groove binder probes. Overall, 85/102 (83.3 %) stray cats tested positive for feline panleukopenia virus (FPV) DNA and one cat was co-infected with canine parvovirus-2 type a. Sequence analysis of the complete capsid region of 15 Nigerian FPV strains revealed that they were up to 99.9 % similar to the American reference strain FPV-b at the nucleotide level, and three of them presented amino acid mutations in key capsid residues. This is the first report of identification and molecular characterization of FPV strains in cats in Nigeria. The high prevalence of the virus emphasizes the need for constant surveillance of the circulation of parvoviruses in Nigeria and underscores the need to deploy an effective vaccination strategy.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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