Exploring Renal Malignancies in Saudi Arabia: Insights from a Tertiary Care Center Study.

Autor: Alasker A; College of Medicine, King Saud bin Abdulaziz University for Health Sciences.; Department of Urology, King Abdulaziz Medical City.; Department of Medicine, King Abdullah International Medical Research Center., Alnafisah TR; College of Medicine, King Saud bin Abdulaziz University for Health Sciences., Alghafees M; College of Medicine, King Saud bin Abdulaziz University for Health Sciences., Sabbah BN; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Shafqat A; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Alhaider A; Department of Urology, King Abdulaziz Medical City., Alsayyari A; Department of Urology, King Abdulaziz Medical City., Althonayan N; Department of Urology, King Abdulaziz Medical City., AlOtaibi M; College of Medicine, King Saud bin Abdulaziz University for Health Sciences., Aldokhel FT; College of Medicine, King Saud bin Abdulaziz University for Health Sciences., Ofisan SB; College of Medicine, Prince Sattam Bin Abdulaziz University. Al-Kharj, Saudi Arabia., Alawad SA; College of Medicine, King Saud bin Abdulaziz University for Health Sciences.
Jazyk: angličtina
Zdroj: Journal of kidney cancer and VHL [J Kidney Cancer VHL] 2023 Dec 18; Vol. 10 (4), pp. 13-19. Date of Electronic Publication: 2023 Dec 18 (Print Publication: 2023).
DOI: 10.15586/jkcvhl.v10i4.289
Abstrakt: This retrospective study aims to describe the characteristics of renal cell carcinoma (RCC) in Saudi Arabia, in terms of epidemiology, clinical presentation, tumor subtype, Fuhrman grade, tumor size and stage, and overall survival. A total of 431 adult patients with a histopathological diagnosis of RCC between 2015 and 2023 were included in the analysis. Most patients (72.4%) had clear cell tumors, followed by chromophobe (15.1%) and papillary (12.5%) subtypes. In males, papillary RCC (85.2%) was more common compared to clear cell (59.8%) and chromophobe (67.7%) subtypes. Significant differences were observed in median body mass index (BMI) across tumor subtypes, and papillary tumor patients exhibited the highest incidence of hematuria (33.3%) compared to other subtypes. The Fuhrman grade also varied significantly among RCC types. Survival times were found to be lower for patients with papillary tumors. No significant difference was observed based on patients' nationality. This study can inform clinical decision-making on patient prognosis and management as well as public health efforts aimed at reducing the alarming rise of RCC incidence.
Competing Interests: The authors declare no conflict of interest.
(Copyright: Alghafees M.A., et al.)
Databáze: MEDLINE
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