Utility of the Milan System for Reporting Salivary Gland Cytopathology in Parotid Gland Masses: The Experience of Two Tertiary Centers.

Autor:	Alqaryan S; Department of Otolaryngology, Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, SAU.; Division of Otorhinolaryngology-Head and Neck Surgery, Department of Surgery, King Abdulaziz Medical City Riyadh, Riyadh, SAU., Alsalamah S; Division of Otorhinolaryngology-Head and Neck Surgery, Department of Surgery, King Abdulaziz Medical City Riyadh, Riyadh, SAU., AlHajress R; Department of Otolaryngology, Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, SAU., Alareek L; Department of Otolaryngology, Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, SAU., Alharbi B; Department of Otolaryngology, Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, SAU., Albarrak M; Department of Otolaryngology-Head and Neck Surgery, King Fahad Medical City, Riyadh, SAU., Almayouf M; Department of Otolaryngology-Head and Neck Surgery, King Fahad Medical City, Riyadh, SAU., Aldhahri S; Department of Otolaryngology, Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, SAU., Al Essa M; Department of Otolaryngology, Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, SAU., Al-Qahtani K; Department of Otolaryngology, Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Nov 22; Vol. 15 (11), pp. e49259. Date of Electronic Publication: 2023 Nov 22 (Print Publication: 2023).
DOI:	10.7759/cureus.49259
Abstrakt:	Background The application of fine needle aspiration (FNA) in parotid masses via the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) enhances the diagnosis of these lesions alongside radiological investigations.  Objectives Our objective was to assess the risk of malignancy, sensitivity, specificity, and false positive and negative results for each category of the MSRSGC. Additionally, we assessed the level of agreement between the FNA results using MSRSGC and post-resection histopathological diagnosis. Methods We conducted a retrospective chart review of parotid gland masses that received FNA and postoperative pathological diagnosis at King Saud University Medical City and King Fahad Medical City between 2018 and 2022. We summarized the categorical variables using frequencies and percentages. Results A total of 172 cases met the inclusion criteria. Males encompassed 102 patients (59.3%) of the study sample, and 89 (51.7%) of parotid masses were on the left side. The risk of malignancy for the MSRSGC categories was 37.5% (Category I), 9.0% (II), 50.0% (III), 4.7% (IVa), 50.0% (IVb), 100.0% (V), and 71.0% (VI). FNA had an overall success rate of 81%. The sensitivity was 64% and specificity was 94% for non-neoplastic masses. For benign masses, the sensitivity was 91% and specificity was 66%; however, the sensitivity was 40% and specificity was 97% for malignant lesions. We found that the percentage of agreement between the FNA and final pathology was 80%. Conclusion FNA using MSRSGC is a valuable preoperative clinical tool. However, the low sensitivity rates based on the diagnosis of malignant lesions should alert clinicians not to be overly reliant on biopsy results and instead defer to definitive surgical management. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Alqaryan et al.)
Databáze:	MEDLINE
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