Ten weeks of Capsicum annuum L. extract supplementation did not change adipose tissue-derived hormones, appetite, body composition, and muscle strength when combined with resistance training in healthy untrained men: A clinical trial study.

Autor: Moura E Silva VEL; Immunometabolism of Skeletal Muscle and Exercise Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil., Panissa VLG; Exercise and Immunometabolism Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil., Cholewa JM; Department of Exercise Physiology, University of Lynchburg, Lynchburg, VA, USA., Vieira MM; Immunometabolism of Skeletal Muscle and Exercise Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil; Graduate Program in Movement Science, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil., Antunes BM; Exercise and Immunometabolism Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil; Facultad de Deportes Campus Ensenada, Universidad Autónoma de Baja California, Ensenada, México., Moura RC; Graduate Program in Science and Health, Federal University of Piauí (UFPI), Teresina, PI, Brazil., Rossi PAQ; Exercise and Immunometabolism Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil., Santos MAP; Department of Biophysics and Physiology, Federal University of Piaui, Campus Minister Petrônio Portela, Ininga, Teresina, Piaui, Brazil., Lira FS; Exercise and Immunometabolism Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil., Rossi FE; Immunometabolism of Skeletal Muscle and Exercise Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil; Department of Exercise Physiology, University of Lynchburg, Lynchburg, VA, USA; Graduate Program in Movement Science, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil; Graduate Program in Science and Health, Federal University of Piauí (UFPI), Teresina, PI, Brazil. Electronic address: f.rossi@unesp.br.
Jazyk: angličtina
Zdroj: Nutrition research (New York, N.Y.) [Nutr Res] 2024 Feb; Vol. 122, pp. 33-43. Date of Electronic Publication: 2023 Dec 05.
DOI: 10.1016/j.nutres.2023.11.010
Abstrakt: Capsiate (CAP) is a nonpungent capsaicin analog (Capsicum annuum L. extract) that has been studied as a potential antiobesity agent. However, the interaction between chronic CAP supplementation and resistance training is not clear. The purpose of this study was to examine the changes in adipose tissue-derived hormones, body composition, appetite, and muscle strength after 10 weeks of resistance training, combined with chronic CAP supplementation in healthy untrained men. We hypothesized that CAP could induce higher benefits when combined with resistance training after 10 weeks of intervention compared to resistance training alone. Twenty-four young men (age, 22.0 ± 2.9) were randomized to either capsiate supplementation (CAP = 12 mg/day) or placebo (PL), and both groups were assigned to resistance training. Body composition, leptin and adiponectin concentrations, subjective ratings of appetite, energy intake, and exercise performance were assessed at before and after 10 weeks of progressive resistance training. There was a significant increase in body mass (P < .001), fat-free mass (CAP: 58.0 ± 7.1 vs. post, 59.7 ± 7.1 kg; PL: pre, 58.4 ± 7.3 vs. post, 59.8 ± 7.1 kg; P < .001), resting metabolic rate (CAP: pre, 1782.9 ± 160.6 vs. post, 1796.3 ± 162.0 kcal; PL: pre, 1733.0 ± 148.9 vs. post, 1750.5 ± 149.8 kcal; P < .001), maximal strength at 45 leg press (P < .001) and bench press (P < .001) in both groups, but no significant (P > .05) supplementation by training period interaction nor fat mass was observed. For subjective ratings of appetite, energy intake, leptin, and adiponectin, no significant effect of supplementation by training period interaction was observed (P > .05). In conclusion, 10 weeks of resistance training increased total body weight, muscle mass, and maximum strength in healthy untrained men; however, CAP supplementation (12 mg, 7 days per week) failed to change adipose tissue-derived hormones, appetite, body composition and muscle strength in this population. Registered under Brazilian Registry of Clinical Trials (RBR-8cz9kfq).
Competing Interests: Author Declarations None
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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