| Autor: |
La Monica MB; The Center for Applied Health Sciences, Canfield, OH 44406, USA., Raub B; The Center for Applied Health Sciences, Canfield, OH 44406, USA., Ziegenfuss EJ; The Center for Applied Health Sciences, Canfield, OH 44406, USA., Hartshorn S; The Center for Applied Health Sciences, Canfield, OH 44406, USA., Grdic J; The Center for Applied Health Sciences, Canfield, OH 44406, USA., Gustat A; The Center for Applied Health Sciences, Canfield, OH 44406, USA., Sandrock J; The Center for Applied Health Sciences, Canfield, OH 44406, USA., Ziegenfuss TN; The Center for Applied Health Sciences, Canfield, OH 44406, USA. |
| Jazyk: |
angličtina |
| Zdroj: |
Nutrients [Nutrients] 2023 Dec 06; Vol. 15 (24). Date of Electronic Publication: 2023 Dec 06. |
| DOI: |
10.3390/nu15245018 |
| Abstrakt: |
The aim of this study was to assess the effects of guayusa extract and Nordic Lion's Mane (LM) on cognition. Using a randomized, double-blind, placebo-controlled, crossover design, we examined the effects of a single dose of 650 mg guayusa extract (AMT: AmaTea ® Max) vs. 1 g Nordic-grown Lion's Mane (LM) vs. placebo (PL). Participants attended three testing visits consisting of neuropsychological tests (Go/No-go, N-Back, and Serial 7 s tasks) assessing performance, subjective assessments of cognitive perception, and vital signs. Each assessment was measured at baseline (pre-ingestion) and 1 and 2 h post ingestion. AMT significantly ( p ≤ 0.05) improved the number of attempts during Serial 7s, total score, number of correct responses, total number of responses, and reaction time during N-Back and improved Go stimulus reaction time, but it reduced the percentage of correct responses in the No-go stimulus response during Go/No-go. LM significantly ( p ≤ 0.05) improved the number of attempts during Serial 7s and reaction time during N-Back and improved Go stimulus reaction time in Go/No-go. AMT improved mental clarity, focus, concentration, mood, and productivity at 1 and 2 h ( p < 0.05); the ability to tolerate stress at 1 h; and had greater ratings than LM and PL for mental clarity, focus, concentration, and productivity. PL improved focus and concentration at 1 h from baseline ( p ≤ 0.05). AMT and LM improved subjective ratings of "happiness compared to peers" and "getting the most out of everything" ( p < 0.05); however, this occurred earlier in LM (i.e., 1 h post ingestion). AMT uniquely elevated blood pressure from baseline. AMT significantly improved cognitive performance and self-perceived cognitive indices of affect over a 2 h period and perceptions of happiness 2 h post ingestion. In comparison, LM helped improve working memory, complex attention, and reaction time 2 h post ingestion and perceptions of happiness over a 2 h period. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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