Case report and mini-review: Sarcina ventriculi in the stomach of an 80-year-old female.

Autor: Kirmaier A; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Kubiak J; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Mahler L; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Qian X; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Wu L; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Ono Y; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Riedel S; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA., Medline A; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Yang X; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Elamin S; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Beth, Israel Deaconess Medical Center, Boston, MA, USA., Afdhal N; Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Beth, Israel Deaconess Medical Center, Boston, MA, USA., Arnaout R; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Division of Clinical Informatics, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA. Electronic address: rarnaout@bidmc.harvard.edu.
Jazyk: angličtina
Zdroj: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2024 Feb; Vol. 108 (2), pp. 116137. Date of Electronic Publication: 2023 Nov 17.
DOI: 10.1016/j.diagmicrobio.2023.116137
Abstrakt: Sarcina ventriculi, also known as Zymosarcina ventriculi and, incorrectly, as Clostridium ventriculi, is rarely encountered in clinical settings. A patient with a complicated gastrointestinal (GI) history, who was acutely presenting with small-bowel obstruction, was found to be colonized by S. ventriculi. The distinctive morphology of this species, with large Gram-variable cocci (up to 3 µm) arranged in two-by-two cuboid clusters reaching up to 20 µm, was key in identifying this bacterium in a stomach biopsy specimen. Sarcina ventriculi appears to be ubiquitously found in nature, and related bacterial species can cause GI-related disease in various animals. Clinical manifestations in humans are broad and often related to other underlying comorbidities. Isolation of S. ventriculi in the laboratory requires anaerobic culture on select media but its absence from standard MALDI-TOF databases complicates identification. Susceptibility data do not exist, so empiric treatment is the only option for this rare pathogen.
Competing Interests: Declaration of Competing Interest The authors declare there is no conflict of interests.
(Copyright © 2023. Published by Elsevier Inc.)
Databáze: MEDLINE
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