Association of fetal ultrasound anthropometric parameters with neurodevelopmental outcomes at 24 months of age.

Autor: Karantha SC; Centre for Health Research and Development, Society for Applied Studies, New Delhi, India., Upadhyay RP; Centre for Health Research and Development, Society for Applied Studies, New Delhi, India., Jain A; Hamdard Institute of Medical Sciences and Research, New Delhi, India., Bhandari N; Centre for Health Research and Development, Society for Applied Studies, New Delhi, India., Dhabhai N; Centre for Health Research and Development, Society for Applied Studies, New Delhi, India., Sapra S; Centre for Health Research and Development, Society for Applied Studies, New Delhi, India., Sharma S; Centre for Health Research and Development, Society for Applied Studies, New Delhi, India., Chowdhury R; Centre for Health Research and Development, Society for Applied Studies, New Delhi, India., Taneja S; Centre for Health Research and Development, Society for Applied Studies, New Delhi, India.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2023 Dec 22; Vol. 18 (12), pp. e0296215. Date of Electronic Publication: 2023 Dec 22 (Print Publication: 2023).
DOI: 10.1371/journal.pone.0296215
Abstrakt: Background: There is a paucity of studies which have examined associations between ultrasound based fetal anthropometric parameters and neurodevelopment in all infants. We examined the association between ultrasound based fetal anthropometric parameters and neurodevelopment in all infants through a secondary analysis of data collected in a large community based randomized controlled trial.
Methods: A total of 1465 mother-child dyads were included. Ultrasound based fetal anthropometric parameters which included the head circumference (HC), abdominal circumference (AC), femur length (FL), biparietal diameter (BPD) and transcerebellar diameter (TCD) were collected at 26-28 weeks of gestation and their association with neurodevelopment at 24 months of age was examined.
Results: Only the transcerebellar diameter z score was positively associated +0.54 units (95% CI: 0.15, 0.93) with motor composite score. When the neurodevelopment outcomes were analyzed as categorical, none of the fetal variables were associated with risk of moderate to severe neurodevelopment impairment.
Conclusion: The findings suggest that transcerebellar diameter could be useful for early prediction of neurodevelopmental outcomes in childhood.
Clinical Trial Registration: Clinical trial registration of Women and Infants Integrated Interventions for Growth Study Clinical Trial Registry-India, #CTRI/2017/06/008908; Registered on: 23/06/2017, (http://ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=19339&EncHid=&userName=society%20for%20applied%20studies).
Competing Interests: The authors declare that they have no competing interests.
(Copyright: © 2023 Karantha et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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