Adherence to Anti-Malarial Treatment in Malaria Endemic Areas of Bangladesh.

Autor:	Hossain MS; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh., Matin MA; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh., Ferdous NN; Bangladesh Rural Advancement Committee (BRAC) Health Programme, BRAC, Dhaka 1212, Bangladesh., Hasan A; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh., Sazed SA; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh., Neogi AK; Bangladesh Rural Advancement Committee (BRAC) Health Programme, BRAC, Dhaka 1212, Bangladesh., Chakma S; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh., Islam MA; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh., Khan AA; Directorate General of Health Services (DGHS), Ministry of Health and Family Welfare, Government of Bangladesh, Dhaka 1212, Bangladesh., Haque ME; Directorate General of Health Services (DGHS), Ministry of Health and Family Welfare, Government of Bangladesh, Dhaka 1212, Bangladesh., Islam S; Bangladesh Rural Advancement Committee (BRAC) Health Programme, BRAC, Dhaka 1212, Bangladesh., Islam MN; Directorate General of Health Services (DGHS), Ministry of Health and Family Welfare, Government of Bangladesh, Dhaka 1212, Bangladesh., Khan WA; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh., Islam MA; Bangladesh Rural Advancement Committee (BRAC) Health Programme, BRAC, Dhaka 1212, Bangladesh., Haque R; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh., Alam MS; Infectious Diseases Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh.
Jazyk:	angličtina
Zdroj:	Pathogens (Basel, Switzerland) [Pathogens] 2023 Nov 27; Vol. 12 (12). Date of Electronic Publication: 2023 Nov 27.
DOI:	10.3390/pathogens12121392
Abstrakt:	Ensuring adherence to antimalarial treatment is crucial for achieving a radical cure and elimination of malaria, especially in hard-to-reach areas. We conducted this study to assess the current scenario of drug adherence in four endemic sub-districts of Bangladesh. Among 110 enrolled participants, 70% were mono-infected with Plasmodium falciparum and the remaining 30% with P. vivax . The overall treatment adherence frequency was 92.7% (95% CI: 83.0-96.3%). A total of eight participants were found to be nonadherent to treatment and all of them were from Bandarban. Level of nonadherence was equally observed in two age groups: 11-17 and 18+ years. However, male participants ( n = 6) were found to be more nonadherent than females ( n = 2). Among 7.3% with nonadherence to treatment, a single participant with P. falciparum mono-infection refused to take medication and became nonadherent. Remaining participants stated that they were feeling well and going to work, thus leaving treatment course uncompleted. Although overall compliance with malaria medication seems good, a gradual increase in noncompliance to P. vivax malaria treatment suggests that the National Malaria Elimination Program must be enhanced and monitored to fulfil the projected malaria elimination goal before 2030 from Bangladesh.
Databáze:	MEDLINE
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