Tongue electrical impedance myography correlates with functional, neurophysiologic, and clinical outcome measures in long-term oropharyngeal cancer survivors with and without hypoglossal neuropathy: An exploratory study.

Autor: Hansen NJ; Department of Electrical and Computer Engineering, The University of Utah, Salt Lake City, Utah, USA., Woodman K; Department of Neurology, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA., Buoy S; Department of Head and Neck Surgery, Division of Surgery, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA., Mao S; Department of Head and Neck Surgery, Division of Surgery, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA., Barbon CEA; Department of Head and Neck Surgery, Division of Surgery, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA., Lai SY; Department of Head and Neck Surgery, Division of Surgery, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA.; Division of Radiation Oncology, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA., Fuller CD; Division of Radiation Oncology, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA., Hutcheson KA; Department of Head and Neck Surgery, Division of Surgery, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA.; Division of Radiation Oncology, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA., Sanchez B; Department of Electrical and Computer Engineering, The University of Utah, Salt Lake City, Utah, USA.
Jazyk: angličtina
Zdroj: Head & neck [Head Neck] 2024 Mar; Vol. 46 (3), pp. 581-591. Date of Electronic Publication: 2023 Dec 22.
DOI: 10.1002/hed.27618
Abstrakt: Background: This pilot study analyzed correlations between tongue electrical impedance myography (EIM), standard tongue electromyography (EMG), and tongue functional measures in N = 4 long-term oropharyngeal cancer (OPC) survivors.
Methods: Patients were screened for a supportive care trial (NCT04151082). Hypoglossal nerve function was evaluated with genioglossus needle EMG, functional measures with the Iowa oral performance instrument (IOPI), and multi-frequency tissue composition with tongue EIM.
Results: Tongue EIM conductivity was higher for patients with EMG-confirmed cranial nerve XII neuropathy than those without (p = 0.005) and in patients with mild versus normal EMG reinnervation ratings (16 kHz EIM: p = 0.051). Tongue EIM correlated with IOPI strength measurements (e.g., anterior maximum isometric lingual strength: r 2  = 0.62, p = 0.020).
Conclusions: Tongue EIM measures related to tongue strength and the presence of XII neuropathy. Noninvasive tongue EIM may be a convenient adjunctive biomarker to assess tongue health in OPC survivors.
(© 2023 Wiley Periodicals LLC.)
Databáze: MEDLINE
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