Paying attention to the value of thrombelastography and the impact of postreperfusion syndrome on outcomes of liver transplantation.
| Autor: | Wu YL; Department of Anesthesiology, Tianjin First Central Hospital, Tianjin 300192, China., Che L; Department of Anesthesiology, Tianjin First Central Hospital, Tianjin 300192, China., Weng YQ; Department of Anesthesiology, Tianjin First Central Hospital, Tianjin 300192, China. wyq2023@nankai.edu.cn. |
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| Jazyk: | angličtina |
| Zdroj: | World journal of gastroenterology [World J Gastroenterol] 2023 Dec 14; Vol. 29 (46), pp. 6092-6094. |
| DOI: | 10.3748/wjg.v29.i46.6092 |
| Abstrakt: | Only limited information is available about the connection between massive blood transfusion and postoperative survival rates in pediatric liver transplantation. The aim of Gordon's study was to examine the potential impact of perioperative transfusion on postoperative complications and death in young children receiving pediatric living-donor liver transplantation (PLDLT). The authors concluded that transfusion of a red blood cell volume higher than 27.5 mL/kg during the perioperative period is associated with a significant increase in short- and long-term postoperative morbidity and mortality after PLDLT. However, viscoelastic coagulation monitoring was not utilized in the study; instead, only conventional coagulation monitoring was conducted. Overall, the choice of blood coagulation monitoring method during blood transfusion can have a significant impact on patient prognosis. Several studies have shown that the viscoelastic coagulation testing such as thrombelastography (TEG) is highly sensitive and accurate for diagnosing coagulation dysfunction. Indeed, a TEG-guided blood transfusion strategy can improve prognosis. Moreover, postreperfusion syndrome is one of the most common complications of liver transplantation and an important factor affecting the prognosis of patients and should also be included in regression analysis. Competing Interests: Conflict-of-interest statement: The authors declare no conflict of interest for this article. (©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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