Driving-related cognitive skills during antidepressant transcranial direct current stimulation: results in a subsample from the DepressionDC trial.
| Autor: | Burkhardt G; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany., Goerigk S; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.; Charlotte Fresenius Hochschule, University of Psychology, Munich, Germany., Dechantsreiter E; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany., Bulubas L; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany., Soldini A; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany., Zwanzger P; kbo-Inn-Salzach-Klinikum, Clinical Center for Psychiatry, Psychotherapy, Psychosomatic Medicine, Geriatrics and Neurology, Wasserburg am Inn, Germany., Diemer J; kbo-Inn-Salzach-Klinikum, Clinical Center for Psychiatry, Psychotherapy, Psychosomatic Medicine, Geriatrics and Neurology, Wasserburg am Inn, Germany., Padberg F; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany., Brunnauer A; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.; kbo-Inn-Salzach-Klinikum, Clinical Center for Psychiatry, Psychotherapy, Psychosomatic Medicine, Geriatrics and Neurology, Wasserburg am Inn, Germany., Kumpf U; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany. |
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| Jazyk: | angličtina |
| Zdroj: | Frontiers in psychiatry [Front Psychiatry] 2023 Dec 07; Vol. 14, pp. 1255415. Date of Electronic Publication: 2023 Dec 07 (Print Publication: 2023). |
| DOI: | 10.3389/fpsyt.2023.1255415 |
| Abstrakt: | Therapeutic transcranial direct current stimulation (tDCS) is a well-tolerated neuromodulatory intervention. However, there are currently no data on its impact on driving skills. Therefore, we conducted a validated assessment of driving-related cognitive skills in participants of the DepressionDC trial, a multicenter, randomized-controlled trial investigating the antidepressant effects of 6-week prefrontal tDCS in patients with major depressive disorder (MDD). Twenty-one patients (12 women, active tDCS, n = 11, sham, n = 10) underwent an assessment of driving-related cognitive skills before and after the intervention. Using a Bayesian analysis approach, we found no group differences between active tDCS and sham tDCS in the pre-post treatment changes for visual perception (estimated median difference: 3.41 [-3.17, 10.55 89%-CI], BF Competing Interests: FP has received grants from the German Research Foundation (DFG; grant no. BR 4264/6–1) and the German Federal Ministry of Education and Research (BMBF; grant no. 01EW1903); consulting fees from Brainsway Inc. (Jerusalem, Israel) as a member of the European Scientific Advisory Board and from Sooma (Helsinki, Finland) as a member of the International Scientific Advisory Board; honoraria for workshops from Mag&More GmbH (Munich, Germany); and honoraria for lectures from neuroCare Group (Munich, Germany) and Brainsway Inc. (Jerusalem, Israel); and has received equipment from Mag&More GmbH (Munich, Germany), neuroCare Group (Munich, Germany), and Brainsway Inc. (Jerusalem, Israel). Over the last 3 years. PZ has received speaker fees or honoraria for advisory board participation from Janssen Pharmaceuticals, MedTrix, Hennig, Schwabe, Servier, Sympatient, and Neuraxpharm. All these affiliations have no relevance to the work covered in the manuscript. AB received speakers honoraria, financial research support, and travel grants from Recordati Pharma GmbH and Schuhfried GmbH within the last 3 years. He received royalties from Medizinisch Wissenschaftliche Verlagsgesellschaft Berlin, is a member of the executive board of the Deutsche Gesellschaft für Verkehrsmedizin and in the panel of experts of the Bundesanstalt für Straßenwesen (BASt). The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Burkhardt, Goerigk, Dechantsreiter, Bulubas, Soldini, Zwanzger, Diemer, Padberg, Brunnauer and Kumpf.) |
| Databáze: | MEDLINE |
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