Effects of exogenous bile acids (BAs) on growth, lipid profile, digestive enzymes, and immune responses of thinlip mullet, Liza ramada.

Autor: Abdel-Tawwab M; Department of Fish Biology and Ecology, Central Laboratory for Aquaculture Research, Agriculture Research Center, Abbassa, Abo-Hammad, Sharqia, Egypt., Abdel-Latif HMR; Department of Poultry and Fish Diseases, Faculty of Veterinary Medicine, Alexandria University, Alexandria, 22758, Egypt. hmhany@alexu.edu.eg., Basuini MFE; Animal Production Department, Faculty of Agriculture, Tanta University, Tanta, 31527, Egypt.; Faculty of Desert Agriculture, King Salman International University, South Sinai, 46618, Egypt., El-Nokrashy AM; Department of Aquaculture, Faculty of Aquatic and Fisheries Science, Kafrelsheikh University, Kafr Elsheikh, Egypt., Khaled AA; Animal and Fish Production Department, Faculty of Agriculture (Saba Basha), Alexandria University, Alexandria, Egypt., Kord M; Central Laboratory for Agricultural Climate, ARC, Giza, Egypt., Soliman AA; National Institute of Oceanography and Fisheries (NIOF), Cairo, Egypt., Zaki M; Animal Production Department, Faculty of Agriculture, Alexandria University, Alexandria, Egypt., Nour AE; Animal Production Department, Faculty of Agriculture, Alexandria University, Alexandria, Egypt., Labib EMH; Utilization of By-Products Department, Animal Production Research Institute, Agriculture Research Center, Ministry of Agriculture and Land Reclamation, Dokki, Giza, Egypt., Khalil HS; Aquaculture Department, Faculty of Fish Resources, Suez University, Suez, 43221, Egypt. halasaber2011@yahoo.com.; College of Fisheries and Aquaculture Technology, Arab Academy for Science, Technology, and Maritime Transport, Alexandria, Egypt. halasaber2011@yahoo.com.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 Dec 18; Vol. 13 (1), pp. 22875. Date of Electronic Publication: 2023 Dec 18.
DOI: 10.1038/s41598-023-49788-6
Abstrakt: An eight-week trial was designed to explore the dietary effects of commercially purchased exogenous bile acids (BAs) on growth, whole-body composition, lipid profile, intestinal digestive enzymes, liver function enzymes, oxidative stress biomarkers, and serum immunity of thinlip mullet, Liza ramada. Four triplicate groups (10.50 ± 0.05 g) were fed four soybean meal (SBM)-based diets supplied with several BAs levels at 0 (control), 50, 130, or 350 mg/kg feed. Results indicated that the growth was significantly increased in groups fed BAs-based diets, especially at 130 mg/kg feed. The body composition analysis showed that feeding fish on diets supplied with BAs up to 130 mg/kg decreased moisture (%) alongside increased crude protein (%). However, the body composition of fish fed a diet with 350 mg BAs/kg had the lowest moisture (%) and the highest crude protein (%). Moreover, there were significant increases in the intestinal (protease, α-amylase, and lipase) enzyme activities in the groups supplied with BAs up to 130 mg BAs/kg. Liver function enzymes (aspartate aminotransferase and alanine aminotransferase enzyme activities) were significantly decreased in BAs-supplemented groups compared to those fed the BAs-free group. On the other hand, the control group had higher total cholesterol, triglycerides, and low-density lipoprotein alongside the lower high-density lipoprotein than BAs-supplemented groups, especially at 350 mg BAs/kg feed. BAs significantly decreased hepatic malondialdehyde concentrations and increased the activity of hepatic catalase, superoxide dismutase, and total antioxidant capacity compared with those reared on the control diet. Serum lysozyme, respiratory burst, and alternative complement activities were significantly increased in BAs-supplied groups, particularly in the group supplied with 130 mg BAs/kg compared to those fed on the control diet. Accordingly, our findings recommend that including 130 mg BAs/kg in an SBM-based diet enhanced the growth, digestive enzyme activities, and liver functions, alleviated oxidative stress, boosted serum immunity, and lowered lipid metabolites in thinlip mullet. These findings will be beneficial for improving the quality of feed prepared for feeding mullets and an effective alternative strategy to support mullet farming.
(© 2023. The Author(s).)
Databáze: MEDLINE
Externí odkaz: