Visualization of deglutition and gastroesophageal reflux using real-time MRI: a standardized approach to image acquisition and assessment.

Autor: Biggemann L; Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany. lorenz.biggemann@med.uni-goettingen.de., Uhlig J; Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany., Streit U; Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.; Department of Radiology, Klinikum Rechts Der Isar, School of Medicine, Technical University of Munich, München, Germany., Al-Bourini O; Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany., Wedi E; Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany.; Department of Gastroenterology, Gastrointestinal Oncology and Interventional Endoscopy, Sana Klinikum, Offenbach, Germany., Amanzada A; Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany., Ellenrieder V; Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen, Germany., Rühlmann F; Department of General, Visceral, and Paediatric Surgery, University Medical Center, Göttingen, Germany., Ghadimi M; Department of General, Visceral, and Paediatric Surgery, University Medical Center, Göttingen, Germany., Frahm J; Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Uecker M; Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.; Institute of Biomedical Imaging, Graz University of Technology, Graz, Austria.; Cluster of Excellence 'Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany., Seif Amir Hosseini A; Department of Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 Dec 21; Vol. 13 (1), pp. 22854. Date of Electronic Publication: 2023 Dec 21.
DOI: 10.1038/s41598-023-49776-w
Abstrakt: This study aims to develop a standardized algorithm for gastroesophageal image acquisition and diagnostic assessment using real-time MRI. Patients with GERD symptoms undergoing real-time MRI of the esophagus and esophagogastric junction between 2015 and 2018 were included. A 10 ml bolus of pineapple juice served as an oral contrast agent. Patients performed Valsalva maneuver to provoke reflux and hiatal hernia. Systematic MRI assessment included visual presence of achalasia, fundoplication failure in patients with previous surgical fundoplication, gastroesophageal reflux, and hiatal hernia. A total of 184 patients (n = 92 female [50%], mean age 52.7 ± 15.8 years) completed MRI studies without adverse events at a mean examination time of 15 min. Gastroesophageal reflux was evident in n = 117 (63.6%), hiatal hernia in n = 95 (52.5%), and achalasia in 4 patients (2.2%). Hiatal hernia was observed more frequently in patients with reflux at rest (n = 67 vs. n = 6, p < 0.01) and during Valsalva maneuver (n = 87 vs. n = 8, p < 0.01). Real-time MRI visualized a morphologic correlate for recurring GERD symptoms in 20/22 patients (90%) after fundoplication procedure. In a large-scale single-center cohort of patients with GERD symptoms undergoing real-time MRI, visual correlates for clinical symptoms were evident in most cases. The proposed assessment algorithm could aid in wider-spread utilization of real-time MRI and provides a comprehensive approach to this novel imaging modality.
(© 2023. The Author(s).)
Databáze: MEDLINE
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