| Autor: |
Silva CF; Universidade Federal da Bahia - UFBA, Instituto de Ciências da Saúde - ICS, Laboratório de Bioengenharia Tecidual e Biomateriais - LBTB, Salvador, BA, Brasil., Felzemburgh VA; Universidade Federal da Bahia - UFBA, Instituto de Ciências da Saúde - ICS, Laboratório de Bioengenharia Tecidual e Biomateriais - LBTB, Salvador, BA, Brasil., Vasconcelos LQ; Universidade Federal da Bahia - UFBA, Instituto de Ciências da Saúde - ICS, Laboratório de Bioengenharia Tecidual e Biomateriais - LBTB, Salvador, BA, Brasil., Nunes VLC; Universidade Federal da Bahia - UFBA, Faculdade de Medicina da Bahia - FMB, Salvador, BA, Brasil., Barbosa Júnior AA; Instituto de Patologia Geral e Cutânea - IPAC, Salvador, BA, Brasil., Giglioti AF; Braile Biomédica, São José do Rio Preto, SP, Brasil., Araújo RPC; Universidade Federal da Bahia - UFBA, Instituto de Ciências da Saúde - ICS, Laboratório de Bioengenharia Tecidual e Biomateriais - LBTB, Salvador, BA, Brasil., Miguel FB; Universidade Federal da Bahia - UFBA, Instituto de Ciências da Saúde - ICS, Laboratório de Bioengenharia Tecidual e Biomateriais - LBTB, Salvador, BA, Brasil., Meneses JVL; Sociedade Brasileira de Cirurgia Plástica - SBCP, São Paulo, SP, Brasil., Rosa FP; Universidade Federal da Bahia - UFBA, Instituto de Ciências da Saúde - ICS, Laboratório de Bioengenharia Tecidual e Biomateriais - LBTB, Salvador, BA, Brasil. |
| Abstrakt: |
Bovine pericardium (BP) has been used as a biomaterial for several decades in many medical applications particularly due to its mechanical properties and the high collagen content. In the acellular form it favors faster tissue repair, providing a three-dimensional support for cellular and vascular events observed during tissue repair and due, to a low elastin content, may favor its use as a breast implant cover, resulting in a low possibility of contracture of the biomaterial, preventing the appearance of irregularities during the reconstruction process. Thus, the aim of this study was to evaluate, histomorphologically, the behavior of acellularized bovine pericardium (ABP) as a mammary implant cover in rats. For this purpose, 16 animals were divided into two groups, with eight animals at each biological point: 7 and 15 days after surgery. Of the 16 animals, 32 specimens were obtained: 16 in the experimental group (EG) and 16 in the control group (CG). Throughout this study, none of the studied groups had postoperative complications. Results: The histomorphological results showed, in the two biological points, both in the EG and in the CG, chronic inflammatory infiltrate, leukocyte fibrin exudate, formation of granulation tissue and deposition of collagen fibers, more evident in the EG, regressive along the biological points. At 15 days, the implanted ABP showed initial biointegration with the fibrous capsule and surrounding tissues of the recipient bed. Conclusion: These results indicate that the due to the observed favorable tissue response ABP may be of potential use as a breast implant cover. |
