Comparison of the Polyamine Content of Five Spring Flowers with Wheat Germ as a Rich Anti-aging Polyamine Source for Preparation of Nutraceutical Products.

Autor:	Mohajeri M; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Ayatollahi SA; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Goli M; Department of Food Science and Technology, Laser and Biophotonics in Biotechnologies Research center, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran., Mokhtari S; Central Research Laboratories, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Khandan M; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Nasiri A; Vice-Chancellor for Food and Drug Affairs, Shahid Beheshti University of Medical Science, Tehran, Iran., Kobarfard F; Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jazyk:	angličtina
Zdroj:	Iranian journal of pharmaceutical research : IJPR [Iran J Pharm Res] 2023 Apr 25; Vol. 22 (1), pp. e134938. Date of Electronic Publication: 2023 Apr 25 (Print Publication: 2023).
DOI:	10.5812/ijpr-134938
Abstrakt:	Polyamines prolong longevity due to their role in cell proliferation and are regarded as an essential group of anti-aging substances that reduce the risk of cardiovascular, neurological, and chronic inflammatory illnesses, as well as cancer. Because of its importance in growth and tissue regeneration, discovering polyamine-rich sources has gotten a lot of interest. Given the role of polyamines in controlling plant growth and physiological changes in the spring after cold winter stress, high polyamine concentrations in quickly growing plant tissues such as flowers, blossoms, and germs are possible. Based on this premise, five different spring flowers were selected and isolated from relevant plants, dried, and then quantified for the first time using an accurate, simple, and repeatable quantification method, liquid chromatography-tandem mass spectrometry. According to the amount of spermidine found in the samples investigated in this study, dried flower powders of Wisteria sinensis (244.18 µg/g), Lonicera caprifolium (217.28 µg/g), and Jasminum officinale (200.33 µg/g) appear to be a good source of spermidine. With additional research, W. sinensis dried flower powder is a good source of polyamines, whereas L. caprifolium and J. officinale dried flower powders are recommended as a rich source of spermidine for the preparation of natural supplements for people over the age of 30 to improve cell proliferation and anti-aging. Competing Interests: The authors declare that they do not have any conflict of interest and that the study does not involve any human or animal testing. (Copyright © 2023, Mohajeri et al.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu