Detection and phylogenetic analysis of contemporary H14N2 Avian influenza A virus in domestic ducks in Southeast Asia (Cambodia).

Autor:	Siegers JY; Virology Unit, Institute Pasteur du Cambodge, Phnom Penh, Cambodia., Wille M; Centre for Pathogen Genomics, Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia.; WHO Collaborating Centre for Reference and Research on Influenza, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Australia., Yann S; Virology Unit, Institute Pasteur du Cambodge, Phnom Penh, Cambodia., Tok S; Virology Unit, Institute Pasteur du Cambodge, Phnom Penh, Cambodia., Sin S; Virology Unit, Institute Pasteur du Cambodge, Phnom Penh, Cambodia., Chea S; Wildlife Conservation Society, Phnom Penh, Cambodia., Porco A; Wildlife Conservation Society, Phnom Penh, Cambodia., Sours S; Wildlife Conservation Society, Phnom Penh, Cambodia., Chim V; National Animal Health and Production Research Institute, Phnom Penh, Cambodia., Chea S; Virology Unit, Institute Pasteur du Cambodge, Phnom Penh, Cambodia., Chhel K; Virology Unit, Institute Pasteur du Cambodge, Phnom Penh, Cambodia., Tum S; National Animal Health and Production Research Institute, Phnom Penh, Cambodia., Sorn S; National Animal Health and Production Research Institute, Phnom Penh, Cambodia., Hak M; Food and Agriculture Organization of the United Nations Country Office, Phnom Penh, Cambodia., Thielen P; Johns Hopkins University Applied Physics Laboratory, Laurel, MD, USA., Dhanasekaran V; School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, People's Republic of China.; HKU-Pasteur Research Pole, School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, People's Republic of China., Karlsson EA; Virology Unit, Institute Pasteur du Cambodge, Phnom Penh, Cambodia.
Jazyk:	angličtina
Zdroj:	Emerging microbes & infections [Emerg Microbes Infect] 2024 Dec; Vol. 13 (1), pp. 2297552. Date of Electronic Publication: 2024 Apr 17.
DOI:	10.1080/22221751.2023.2297552
Abstrakt:	Avian influenza virus (AIV) in Asia is a complex system with numerous subtypes and a highly porous wild birds-poultry interface. Certain AIV subtypes, such as H14, are underrepresented in current surveillance efforts, leaving gaps in our understanding of their ecology and evolution. The detection of rare subtype H14 in domestic ducks in Southeast Asia comprises a geographic region and domestic bird population previously unassociated with this subtype. These H14 viruses have a complex evolutionary history involving gene reassortment events. They share sequence similarity to AIVs endemic in Cambodian ducks, and Eurasian low pathogenicity and high pathogenicity H5Nx AIVs. The detection of these H14 viruses in Southeast Asian domestic poultry further advances our knowledge of the ecology and evolution of this subtype and reinforces the need for continued, longitudinal, active surveillance in domestic and wild birds. Additionally, in vivo and in vitro risk assessment should encompass rare AIV subtypes, as they have the potential to establish in poultry systems.
Databáze:	MEDLINE
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