Q fever, a rare cause of secondary hemophagocytic lymphohistiocytosis.

Autor:	Nieves Salceda JF; Division of Respiratory Medicine, Hospital Universitario Central de Asturias, Spain., Lozano Cuesta P; Division of Respiratory Medicine, Hospital Universitario Central de Asturias, Spain., Hermoso de Mendoza Aristegui S; Division of Respiratory Medicine, Hospital Universitario Central de Asturias, Spain., Fernández-Suárez J; Microbiology Department, Hospital Universitario Central de Asturias, Spain., Madrid Carbajal C; Division of Respiratory Medicine, Hospital Universitario Central de Asturias, Spain., García Clemente MM; Division of Respiratory Medicine, Hospital Universitario Central de Asturias, Spain.
Jazyk:	angličtina
Zdroj:	GMS infectious diseases [GMS Infect Dis] 2023 Dec 06; Vol. 11, pp. Doc05. Date of Electronic Publication: 2023 Dec 06 (Print Publication: 2023).
DOI:	10.3205/id000085
Abstrakt:	Hemophagocytic lymphohistiocytosis (HLH) is a rare syndrome in which Coxiella burnetii is a very infrequent etiology. We present the case of a 62-year-old male with progressive pulmonary infiltrates, fever, hepatitis, and bicytopenia despite broad spectrum antibiotics. A thorough clinical evaluation led to a high suspicion of Coxiella burnetii infection, subsequently confirmed through a positive serum polymerase chain reaction (PCR) analysis. HLH diagnosis was established based on the fulfillment of 5/8 diagnostic criteria, obviating the need for a bone marrow biopsy. Targeted antibiotic treatment and dexamethasone led to full recovery within two weeks, eliminating the need for stronger immunosuppressive therapy. Competing Interests: The authors declare that they have no competing interests. (Copyright © 2023 Nieves Salceda et al.)
Databáze:	MEDLINE
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