Refractory Cytomegalovirus Colitis Followed by De Novo Inflammatory Bowel Disease Post-Orthotopic Liver Transplantation.

Autor:	Selvan B; Duke University School of Medicine, Durham, NC., Pendse AA; Department of Pathology, Duke University School of Medicine, Durham, NC., Zhang C; Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, NC., Cauthen J; Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, NC., Kappus MR; Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, NC., Messina JA; Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC.
Jazyk:	angličtina
Zdroj:	ACG case reports journal [ACG Case Rep J] 2023 Dec 16; Vol. 10 (12), pp. e01232. Date of Electronic Publication: 2023 Dec 16 (Print Publication: 2023).
DOI:	10.14309/crj.0000000000001232
Abstrakt:	Cytomegalovirus (CMV) and inflammatory bowel disease (IBD) are both immune-mediated complications that affect orthotopic liver transplantation patients. In this report, we present a 60-year-old man who underwent orthotopic liver transplantation for cryptogenic cirrhosis with serologies notable for CMV-seropositive donor and seronegative recipient. His post-transplant course was initially complicated by probable refractory CMV colitis. However, his gastrointestinal symptoms persisted, eventually leading to a diagnosis of post-transplant de novo IBD. The discussion highlights theories regarding the association between CMV and IBD, a topic that has been widely debated for decades. (© 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)
Databáze:	MEDLINE
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