Using a digital tool to detect early changes in everyday functioning in older adults: A pilot study of the Assessment of Smartphone Everyday Tasks (ASSET).

Autor: Dubbelman MA; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA., Hall TC; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA., Levesque IM; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA., Mimmack KJ; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA., Sikkes SAM; Department of Neurology Alzheimer Center Amsterdam Vrije Universiteit Amsterdam Amsterdam The Netherlands.; Faculty of Behavioral and Movement Sciences Clinical Developmental Psychology and Clinical Neuropsychology Vrije Universiteit Amsterdam Amsterdam The Netherlands., Fischer SH; RAND Corporation Boston Massachusetts USA., Rentz DM; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA., Sperling RA; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA., Papp KV; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA., Amariglio RE; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA., Marshall GA; Department of Neurology Massachusetts General Hospital Harvard Medical School Boston Massachusetts USA.; Department of Neurology Center for Alzheimer Research and Treatment Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.
Jazyk: angličtina
Zdroj: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2023 Dec 17; Vol. 15 (4), pp. e12506. Date of Electronic Publication: 2023 Dec 17 (Print Publication: 2023).
DOI: 10.1002/dad2.12506
Abstrakt: Introduction: To investigate the utility of a new digital tool for measuring everyday functioning in preclinical Alzheimer's disease, we piloted the Assessment of Smartphone Everyday Tasks (ASSET) application.
Methods: Forty-six participants (50.3 ± 27.1 years; 67% female; 20 young unimpaired, 17 old unimpaired, 9 mildly cognitively impaired) completed ASSET 7 times. ASSET comprises two main tasks, simulating a Patient Portal and a Calendar. We assessed ASSET's internal consistency, test-retest reliability, and user experience.
Results: ASSET main tasks correlated with each other ( r  = 0.75, 95% confidence interval [CI] = [0.58, 0.86]). Performance on ASSET's Patient Portal related to cognition ( r  = 0.64, 95% CI = [0.42, 0.79]) and observer ratings of everyday functioning ( r  = 0.57, 95% CI = [0.24, 0.79]). Test-retest reliability was good (intraclass correlation coefficient = 0.87, 95% CI = [0.77, 0.93]). Most participants rated their experience with ASSET neutrally or positively.
Discussion: ASSET is a promising smartphone-based digital assessment of everyday functioning. Future studies may investigate its utility for early diagnosis and evaluation of treatment of Alzheimer's disease.
Competing Interests: G.A.M. is a senior associate editor for this journal but was not involved in the journal's peer‐review process nor had access to any information regarding its peer‐review. The other authors report no conflicts of interest pertaining to this manuscript. Author disclosures are available in the supporting information.
(© 2023 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals LLC on behalf of Alzheimer's Association.)
Databáze: MEDLINE
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