Evaluating elimination of mother-to-child transmission of HIV in Suriname: a mixed method study.

Autor: Stijnberg D; Faculty of Medical Sciences Anton de Kom Universiteit van Suriname Paramaribo Suriname Faculty of Medical Sciences, Anton de Kom Universiteit van Suriname, Paramaribo, Suriname., Holband S; National AIDS Program Paramaribo Suriname National AIDS Program, Paramaribo, Suriname., Charles R; Academic Hospital Paramaribo Paramaribo Suriname Academic Hospital Paramaribo, Paramaribo, Suriname., Ulenaers D; Faculty of Medicine and Life Sciences Hasselt University Hasselt Belgium Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium., Schrooten W; Faculty of Medicine and Life Sciences Hasselt University Hasselt Belgium Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium., Adhin MR; Faculty of Medical Sciences Anton de Kom Universiteit van Suriname Paramaribo Suriname Faculty of Medical Sciences, Anton de Kom Universiteit van Suriname, Paramaribo, Suriname.
Jazyk: angličtina
Zdroj: Revista panamericana de salud publica = Pan American journal of public health [Rev Panam Salud Publica] 2023 Dec 18; Vol. 47, pp. e159. Date of Electronic Publication: 2023 Dec 18 (Print Publication: 2023).
DOI: 10.26633/RPSP.2023.159
Abstrakt: Objectives: To evaluate the cascade of care for the elimination of mother-to-child-transmission of human immunodeficiency virus (HIV) in Suriname and identify sociodemographic and clinical factors preventing transmission to exposed infants.
Methods: A mixed-methods study design was used. Antenatal care data from the 2018 cross-sectional multi-indicator cluster survey on 1 026 women aged 15-49 years who had had a live birth in the previous 2 years were used. Furthermore, national data on a cohort of 279 mothers with HIV and their 317 infants born from 2016 to 2018 were evaluated. Additionally, 13 cases of mother-to-child-transmission of HIV were reviewed.
Results: In 89.3% of cases, no mother-to-child HIV transmission occurred. Early cascade steps show that 28.4% of women had unmet family planning needs, 15% had no antenatal visits, 8% delivered outside a health facility, and 71.5% received an HIV test during antenatal care. Of the pregnant women with HIV, 84.2% received antiretroviral therapy, while 95.5% of their infants received HIV prophylactic treatment. Receiving antiretroviral therapy for the mother (odds ratio (OR) 45.4, 95% confidence interval (CI) 9.6-215.3) and the child (OR 145.7, 95% CI 14.4-1477.4) significantly increased the odds of a negative HIV test result in infants. Conversely, living in the interior decreased the odds (OR 0.2, 95% CI 0.4-0.7) compared with urban living.
Conclusions: HIV medication for mothers with HIV and their infants remains key in the prevention of mother-to-child-transmission of HIV. Early prenatal care with follow-up should be strengthened in Suriname.
Databáze: MEDLINE