Cytomegalovirus -Related Gastritis in an Immunocompetent Host Presenting With Infectious Gastroparesis.

Autor:	Solito S; Gastroenterology and GI Endoscopy Unit, Academic Medical Center of Udine, Udine, Italy., Vadalá di Prampero SF; Gastroenterology and GI Endoscopy Unit, Mater Olbia Hospital, Qatar Foundation Endowment & Gemelli Foundation, Olbia, Italy.; Department for Digestive Endoscopy, Ospedale Isola Tiberina - Gemelli Isola, Rome, Italy., Bulajic M; Gastroenterology and GI Endoscopy Unit, Mater Olbia Hospital, Qatar Foundation Endowment & Gemelli Foundation, Olbia, Italy.; Department for Digestive Endoscopy, Ospedale Isola Tiberina - Gemelli Isola, Rome, Italy., Battista S; Department of Pathology, Academic Medical Center of Udine, Udine, Italy., Tomassini G; Gastroenterology and GI Endoscopy Unit, Mater Olbia Hospital, Qatar Foundation Endowment & Gemelli Foundation, Olbia, Italy., Panic N; GI Endoscopy Unit, University Clinic 'Dr Dragisa Misovic - Dedinje', Belgrade, Serbia., Jankovic K; Clinic for Gastroenterohepatology, University Clinical Centre of Belgrade, Belgrade, Serbia., Marino M; Gastroenterology and GI Endoscopy Unit, Academic Medical Center of Udine, Udine, Italy.
Jazyk:	angličtina
Zdroj:	ACG case reports journal [ACG Case Rep J] 2023 Dec 15; Vol. 10 (12), pp. e01231. Date of Electronic Publication: 2023 Dec 15 (Print Publication: 2023).
DOI:	10.14309/crj.0000000000001231
Abstrakt:	Cytomegalovirus (CMV) infection is usually asymptomatic or causes a mild mononucleosis-like syndrome, whereas severe symptoms are rarely reported. We report a case of a 70-year-old woman who was admitted to our center because of severe clinical presentation with anorexia, epigastric pain, nausea, postprandial vomiting, and significant weight loss. Esophagogastroduodenoscopy with biopsies showed ulcerative chronic gastritis with scattered large cells with inclusion bodies. Immunohistochemistry and polymerase chain reaction for CMV-DNA resulted positive. A gastric emptying of solid scintigraphy showed severe gastroparesis. The patient was discharged after 2 months of antiviral therapy completely asymptomatic. To the best of our knowledge, this is the first case of CMV-related gastroparesis in an immunocompetent patient, successfully treated with antiviral therapy. (© 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)
Databáze:	MEDLINE
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