Peripheral magnetic stimulation for chronic peripheral neuropathic pain: A systematic review and meta-analysis.

Autor: Dana E; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.; Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Anesthesia, Intensive Care and Pain Medicine, Meir Medical Center, Kfar Saba, affiliated to the Sackler School of Medicine, Tel Aviv, Israel., Tran C; Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada., Osokin E; Centre for Multimodal Sensorimotor and Pain Research, University of Toronto, Toronto, Ontario, Canada.; Department of Dentistry, Mount Sinai Hospital, Toronto, Ontario, Canada., Westwood D; University of Toronto Centre for the Study of Pain, University of Toronto, Toronto, Ontario, Canada., Moayedi M; Centre for Multimodal Sensorimotor and Pain Research, University of Toronto, Toronto, Ontario, Canada.; Department of Dentistry, Mount Sinai Hospital, Toronto, Ontario, Canada.; University of Toronto Centre for the Study of Pain, University of Toronto, Toronto, Ontario, Canada., Sabhaya P; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.; Mount Sinai Hospital, Toronto, Ontario, Canada., Khan JS; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, Ontario, Canada.; Mount Sinai Hospital, Toronto, Ontario, Canada.
Jazyk: angličtina
Zdroj: Pain practice : the official journal of World Institute of Pain [Pain Pract] 2024 Apr; Vol. 24 (4), pp. 647-658. Date of Electronic Publication: 2023 Dec 16.
DOI: 10.1111/papr.13332
Abstrakt: Objectives: To provide a systematic review of the literature on the effects of peripheral magnetic stimulation (PMS) in the treatment of chronic peripheral neuropathic pain.
Methods: A systematic search of MEDLINE, EMBASE, CENTRAL, CINHAL, Web of Science, and ProQuest was conducted from inception to July 2023 to identify studies of any design published in English language that enrolled adult patients (≥18 years) that received PMS for treatment of a chronic peripheral neuropathic pain disorder (pain > 3 months).
Results: Twenty-three studies were identified which included 15 randomized controlled trials (RCTs), five case series, two case reports, and one non-randomized trial. PMS regimens varied across studies and ranged from 5 to 240 min per session over 1 day to 1 year of treatment. Results across included studies were mixed, with some studies suggesting benefits while others showing no significant differences. Of nine placebo-controlled RCTs, four reported statistically significant findings in favor of PMS use. In the meta-analysis, PMS significantly reduced pain scores compared to control within 0-1 month of use (mean difference -1.64 on a 0-10 numeric rating scale, 95% confidence interval -2.73 to -0.56, p = 0.003, I 2  = 94%, 7 studies [264 participants], very low quality of evidence), but not at the 1-3 months and >3 months of PMS use (very low and low quality of evidence, respectively). Minimal to no adverse effects were reported with PMS use.
Discussion: There is limited and low-quality evidence to make definitive recommendations on PMS usage, however, the available data is encouraging, especially for short-term applications of this novel modality. Large high-quality randomized controlled trials are required to establish definitive efficacy and safety effects of PMS.
(© 2023 World Institute of Pain.)
Databáze: MEDLINE
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