Emerging porcine Enterovirus G infections, epidemiological, complete genome sequencing, evolutionary and risk factor analysis in India.

Autor: Bhat S; Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India., Ansari MI; Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India; Department of Biosciences, Integral University Lucknow, India., Kattoor JJ; Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India; Department of Comparative Pathobiology, Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN 47907, USA., Sircar S; Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India; Department of Animal Sciences, Washington State University, Pullman, WA 99164, USA., Dar PS; Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India., Deol P; Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India; Institute for Modeling Collaboration and Innovation and Department of Biological Sciences, University of Idaho, Moscow, ID 83844, USA., Vinodh Kumar OR; Division of Epidemiology, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India., Thomas P; Division of Bacteriology and Mycology, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India., Ghosh S; Department of Biomedical Sciences, Ross University School of Veterinary Medicine,Basseterre P.O. 334, Saint Kitts and Nevis, West Indies., El Zowalaty ME; Veterinary Medicine and Food Security Research Group, Medical Laboratory Sciences Program, Faculty of Health Sciences, Abu Dhabi Women Campus, Higher Colleges of Technology, Abu Dhabi 41012, United Arab Emirates. Electronic address: elzow005@gmail.com., Malik YS; Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Bareilly 243122, India; College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana 141001, India. Electronic address: malikyps@gmail.com.
Jazyk: angličtina
Zdroj: Virology [Virology] 2024 Feb; Vol. 590, pp. 109906. Date of Electronic Publication: 2023 Oct 16.
DOI: 10.1016/j.virol.2023.109906
Abstrakt: The current study reports the in-depth analysis of the epidemiology, risk factors, and molecular characterization of a complete genome of Enterovirus G (EV-G) isolated from Indian pigs. We analysed several genes of EV-G isolates collected from various provinces in India, using phylogenetic analysis, recombination detection, SimPlot, and selection pressure analyses. Our analysis of 534 porcine faecal samples revealed that 11.61% (62/534) of the samples were positive for EV-G. While the G6 genotype was the most predominant, our findings showed that Indian EV-G strains also clustered with EV-G types G1, G6, G8, and G9. Furthermore, Indian EV-G strains exhibited the highest nucleotide similarity with Vietnamese (81.3%) and Chinese EV-G isolates (80.3%). Moreover, we identified a recombinant Indian EV-G strain with a putative origin from a Japanese isolate and South Korean EV-G isolate. In summary, our findings provide significant insights into the epidemiology, genetic diversity, and evolution of EV-G in India.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this manuscript.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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