Impact of post-stroke aphasia on functional communication, quality of life, perception of health and depression: A case-control study.

Autor: Bueno-Guerra N; Faculty of Psychology, Comillas Pontifical University, Madrid, Spain., Provencio M; Faculty of Psychology, Comillas Pontifical University, Madrid, Spain., Tarifa-Rodríguez A; Universidad Autónoma de Madrid (UAM), Madrid, Spain., Navarro A; Faculty of Psychology, Comillas Pontifical University, Madrid, Spain., Sempere-Iborra C; La Paz University Hospital-Autonomous University of Madrid, Madrid, Spain., Jordi P; La Paz University Hospital-Autonomous University of Madrid, Madrid, Spain., de Celis-Ruiz E; Department of Neurology and Stroke Unit, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain., Alonso de Leciñana M; Department of Neurology and Stroke Unit, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain., Martín-Alonso M; Speech Therapy Unit, Department of Rehabilitation, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain., Rigual R; Department of Neurology and Stroke Unit, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain., Ruiz-Ares G; Department of Neurology and Stroke Unit, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain., Rodríguez-Pardo J; Department of Neurology and Stroke Unit, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain., Virués-Ortega J; School of Psychology, University of Auckland, Auckland, New Zealand., Fuentes B; Department of Neurology and Stroke Unit, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain.
Jazyk: angličtina
Zdroj: European journal of neurology [Eur J Neurol] 2024 Apr; Vol. 31 (4), pp. e16184. Date of Electronic Publication: 2023 Dec 14.
DOI: 10.1111/ene.16184
Abstrakt: Background and Purpose: Post-stroke aphasia is associated with a reduced quality of life (QoL) and higher risk of depression. Few studies have addressed the effect of coping with aphasia. Our aim is to evaluate the impact of post-stroke aphasia on self-reported QoL and symptoms of depression.
Methods: This was a cross-sectional prospective case-control study. Cases involved patients with post-stroke aphasia included in the DULCINEA trial (NCT04289493). Healthy controls were recruited using snowball sampling. All subjects completed the following questionnaires: General Health Questionnaire (GHQ-12), Stroke Aphasia Quality of Life Scale (SAQOL-39), Communicative Activity Log (CAL) and Stroke Aphasic Depression Questionnaire (SADQ-10).
Results: Twenty-three patients (eight women; mean age 62.9 years) and 73 controls (42 women; mean age 53.7 years) were included. Cases scored lower than controls in perception of health (GHQ-12: median 3 [IQR 1; 6] vs. 0 [IQR 0; 2]) and perception of QoL (SAQOL-39: median 3.6 [IQR 3.3; 40] vs. 4.6 [IQR 4.2; 4.8]). Functional communication (CAL: median 135 [IQR 122; 148] vs. 94 [IQR 74; 103]) and SAQOL-39 communication subscale (median 2.7 [IQR 2.1; 3.2] vs. 4.8 [IQR 4.6; 5.0]) were also significantly lower in the case group. Notably, cases reported fewer depressive symptoms than controls (SADQ-10: median 11 [IQR 9; 15] vs. 13 [IQR 11; 16]; p = 0.016). A mediational analysis revealed that the relationship between post-stroke aphasia and depression was not mediated by functional communication.
Conclusions: Although communication difficulties impact the QoL of patients with post-stroke aphasia, such patients report fewer depressive symptoms on the SADQ-10 scale than healthy people, with no differences in scores related to social participation.
(© 2023 The Authors. European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology.)
Databáze: MEDLINE
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