Discharge protocol in acute pancreatitis: an international survey and cohort analysis.
Autor: | Nagy R; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.; Heim Pál National Pediatric Institute, Budapest, Hungary., Ocskay K; Heim Pál National Pediatric Institute, Budapest, Hungary., Sipos Z; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary., Szentesi A; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary., Vincze Á; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary., Czakó L; Department of Medicine, University of Szeged, Szeged, Hungary., Izbéki F; Szent György University Teaching Hospital of Fejér County, Székesfehérvár, Hungary., Shirinskaya NV; Omsk State Medical Information-Analytical Centre, Omsk State Medical University, Omsk, Russia., Poluektov VL; Department of Surgery and Urology, Omsk State Medical University, Omsk, Russia., Zolotov AN; Department of Pathophysiology, Clinical Pathophysiology, Omsk State Medical University, Omsk, Russia., Zhu Y; Department of Gastroenterology, First Affiliated Hospital of Nanchang University, Nanchang, China., Xia L; Department of Gastroenterology, First Affiliated Hospital of Nanchang University, Nanchang, China., He W; Department of Gastroenterology, First Affiliated Hospital of Nanchang University, Nanchang, China., Sutton R; University of Liverpool, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Szatmary P; University of Liverpool, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Mukherjee R; University of Liverpool, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Burridge IS; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Wauchope E; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Francisco E; Surgery Department, Hospital Prof. Ferndo Fonseca, Amadora, Portugal., Aparicio D; Surgery Department, Hospital Prof. Ferndo Fonseca, Amadora, Portugal., Pinto B; Surgery Department, Hospital Prof. Ferndo Fonseca, Amadora, Portugal., Gomes A; Surgery Department, Hospital Prof. Ferndo Fonseca, Amadora, Portugal., Nunes V; Surgery Department, Hospital Prof. Ferndo Fonseca, Amadora, Portugal., Tantau VM; 'Octavin Fodor' Institute of Gastroenterology and Hepartology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, Cluj Napoca, Romania., Sagau ED; 'Octavin Fodor' Institute of Gastroenterology and Hepartology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, Cluj Napoca, Romania., Tantau AI; Gastroenterology Department, 4th Medical Clinic, 'Iuliu Hatieganu' University of Medicine and Pharmacy, Cluj Napoca, Romania., Suceveanu AI; Faculty of Medicine, Ovidius University of Constanta, Constanta, Romania., Tocia C; Faculty of Medicine, Ovidius University of Constanta, Constanta, Romania., Dumitru A; Faculty of Medicine, Ovidius University of Constanta, Constanta, Romania., Pando E; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain., Alberti P; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain., Cirera A; Department of Hepato-Pancreato-Biliary and Transplant Surgery, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain., Molero X; Exocrine Pancreas Research Unit, Hospital Universitari Vall d'Hebron, Institut de Recerca, Universitat Autònoma de Barcelona, CIBEREHD, Barcelona, Spain., Lee HS; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Anam Hospital, Seoul, Republic of Korea., Jung MK; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Anam Hospital, Seoul, Republic of Korea., Kim EJ; Division of Gastroenterology, Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea., Lee S; Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Rebollo MLR; Servicio de Aparato Digestivo Hospital Clínico Universitario Valladolid, Valladolid, Spain., Nistal RB; Servicio de Aparato Digestivo Hospital Clínico Universitario Valladolid, Valladolid, Spain., Santervas SI; Servicio de Aparato Digestivo Hospital Clínico Universitario Valladolid, Valladolid, Spain., Lesko D; 1st Department of Surgery, University Hospital of L. Pasteur, Kosice, Slovak Republic., Soltes M; 1st Department of Surgery, University Hospital of L. Pasteur, Kosice, Slovak Republic., Radonak J; 1st Department of Surgery, University Hospital of L. Pasteur, Kosice, Slovak Republic., Zatorski H; Department of Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland., Małecka-Panas E; Department of Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland., Fabisiak A; Department of Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland., Yaroslav MS; Department of Surgery With a Course of Emergency and Vascular Surgery, Bogomolet National Medical University, Kiev, Ukraine., Mykhailo VM; Department of Surgery With a Course of Emergency and Vascular Surgery, Bogomolet National Medical University, Kiev, Ukraine., Olekcandr AT; Kyiv City Clinical Emergency Hospital, Kiev, Ukraine., Barauskas G; Department of Surgery, Lithuanian University of Health Sciences, Kaunas, Lithuania., Simanaitis V; Department of Surgery, Lithuanian University of Health Sciences, Kaunas, Lithuania., Ignatavicius P; Kyiv City Clinical Emergency Hospital, Kiev, Ukraine., Jinga M; Department of Surgery, Lithuanian University of Health Sciences, Kaunas, Lithuania., Balaban VD; Department of Surgery, Lithuanian University of Health Sciences, Kaunas, Lithuania., Patoni C; 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania., Gong L; 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania., Song K; 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania., Li Y; 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania., Gonçalves TC; Gastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga/Guimarães, Portugal.; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal., Freitas M; Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Macedo V; Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; Gastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga/Guimarães, Portugal., Vornhuelz M; LMU University Hospital, LMU Munich, Munich, Germany., Klauss S; LMU University Hospital, LMU Munich, Munich, Germany., Beyer G; LMU University Hospital, LMU Munich, Munich, Germany., Koksal AS; Department of Gastroenterology, Faculty of Medicine, Sakarya University, Sakarya, Turkey., Tozlu M; Department of Gastroenterology, Faculty of Medicine, Sakarya University, Sakarya, Turkey., Eminler AT; Department of Gastroenterology, Faculty of Medicine, Sakarya University, Sakarya, Turkey., Monclús NT; University Hospital Arnau de Vilanova, Hospital University Santa Maria, Lleida, Spain., Comas EP; University Hospital Arnau de Vilanova, Hospital University Santa Maria, Lleida, Spain., Oballe JAR; University Hospital Arnau de Vilanova, Hospital University Santa Maria, Lleida, Spain., Nawacki Ł; Collegium Medicum, The Jan Kochanowski University in Kielce, Kielce, Poland., Głuszek S; Collegium Medicum, The Jan Kochanowski University in Kielce, Kielce, Poland., Rama-Fernández A; Gastroenterology Department, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain., Galego M; Gastroenterology Department, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain., de la Iglesia D; Gastroenterology Department, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain., Aykut UE; Marmara University Education and Training Hospital, Istanbul, Turkey., Duman DG; Marmara University Education and Training Hospital, Istanbul, Turkey., Aslan R; Marmara University Education and Training Hospital, Istanbul, Turkey., Gherbon A; Discipline of Internal Medicine: Diabetes, Nutrition, Metabolic Diseases and Systemic Rheumatology, Victor Babeş University of Medicine and Pharmacy Timisoara, Timisoara, Romania., Deng L; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Center and West China-Liverpool Biomedical Research Center, West China Hospital, Sichuan University, Chengdu, China., Huang W; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Center and West China-Liverpool Biomedical Research Center, West China Hospital, Sichuan University, Chengdu, China., Xia Q; Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Center and West China-Liverpool Biomedical Research Center, West China Hospital, Sichuan University, Chengdu, China., Poropat G; Department of Gastroenterology, Clinical Hospital Center Rijeka, University of Rijeka, Rijeka, Croatia., Radovan A; Department of Gastroenterology, Clinical Hospital Center Rijeka, University of Rijeka, Rijeka, Croatia., Vranić L; Department of Gastroenterology, Clinical Hospital Center Rijeka, University of Rijeka, Rijeka, Croatia., Ricci C; Division of Pancreatic Surgery, IRCCS, Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy.; Department of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy., Ingaldi C; Division of Pancreatic Surgery, IRCCS, Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy.; Department of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy., Casadei R; Division of Pancreatic Surgery, IRCCS, Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy.; Department of Internal Medicine and Surgery (DIMEC), Alma Mater Studiorum, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy., Negoi I; Emergency Hospital of Bucharest, Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania., Ciubotaru C; Emergency Hospital of Bucharest, Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania., Iordache FM; Emergency Hospital of Bucharest, Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania., Constantinescu G; Emergency Hospital of Bucharest, Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania., Sandru V; Emergency Hospital of Bucharest, Carol Davila University of Medicine and Pharmacy Bucharest, Bucharest, Romania., Altintas E; Gastroenterology Department, Faculty of Medicine, Mersin University, Yenisehir/Mersin, Turkey., Balci HR; Gastroenterology Department, Faculty of Medicine, Mersin University, Yenisehir/Mersin, Turkey., Constantino J; Unidade HBP, Serviço de Cirurgia Geral, Centro Hospitalar Tondela-Viseu, Viseu, Portugal., Aveiro D; Unidade HBP, Serviço de Cirurgia Geral, Centro Hospitalar Tondela-Viseu, Viseu, Portugal., Pereira J; Unidade HBP, Serviço de Cirurgia Geral, Centro Hospitalar Tondela-Viseu, Viseu, Portugal., Gunay S; İzmir Katip Çelebi University Atatürk Training and Research Hospital, Karabaglar/Izmir, Turkey., Misirlioglu Sucan S; İzmir Katip Çelebi University Atatürk Training and Research Hospital, Karabaglar/Izmir, Turkey., Dronov O; General Surgery #1, Bogomolets National Medical University, Kiev, Ukraine., Kovalska I; General Surgery #1, Bogomolets National Medical University, Kiev, Ukraine., Bush N; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India., Rana SS; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India., Chooklin S; Lviv Regional Clinical Hospital, Lviv, Ukraine., Chuklin S; Lviv Regional Clinical Hospital, Lviv, Ukraine., Saizu IA; Clinical Institute Fundeni, Bucharest, Romania., Gheorghe C; 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.; Clinical Institute Fundeni, Bucharest, Romania., Göltl P; Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Hirth M; Department of Medicine II, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Mateescu RB; 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.; Gastroenterology Department, Colentina Clinical Hospital Bucharest, Bucharest, Romania., Papuc G; Gastroenterology Department, Colentina Clinical Hospital Bucharest, Bucharest, Romania., Minkov GA; Department of Surgery, University Hospital, Stara Zagora, Bulgaria., Enchev ET; Department of Surgery, University Hospital, Stara Zagora, Bulgaria., Mastrangelo L; Department of Surgery, AOU Sant'Orsola Malpighi, IRCCS Azienda Ospedaliera Universitaria, Bologna, Italy., Jovine E; Department of Surgery, AOU Sant'Orsola Malpighi, IRCCS Azienda Ospedaliera Universitaria, Bologna, Italy., Chen W; Department of Gastroenterology, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China., Zhu Q; Department of Gastroenterology, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China., Gąsiorowska A; Department of Gastroenterology Medical, University of Lodz, Lodz, Poland., Fabisiak N; Department of Gastroenterology Medical, University of Lodz, Lodz, Poland., Bezmarevic M; Department for Hepatobiliary and Pancreatic Surgery, Clinic for General Surgery, Military Medical Academy, University of Defense, Belgrade, Serbia., Litvin A; Gomel State Medical University, Gomel, Belarus., Mottes MC; Department of Medicine, Gastroenterology, The Pancreas Institute, G.B. Rossi University Hospital, Verona, Italy., Choi EK; Department of Internal Medicine, Jeju National University College of Medicine, Jeju, South Korea., Bánovčin P; Clinic of Internal Medicine - Gastroenterology, JFM CU, Jessenius Faculty of Medicine in Martin (JFM CU), Comenius University in Bratislava, Bratislava, Slovakia., Nosáková L; Clinic of Internal Medicine - Gastroenterology, JFM CU, Jessenius Faculty of Medicine in Martin (JFM CU), Comenius University in Bratislava, Bratislava, Slovakia., Kovacheva-Slavova MD; Department of Gastroenterology, Queen Yoanna University Hospital, Medical University of Sofia, Sofia, Bulgaria., Kchaou A; Habib Bourguiba University Hospital, Sfax, Tunisia., Tlili A; Mohamed Ben Sassi Hospital, Gabes, Tunisia., Marino MV; General Surgery Department, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy., Kusnierz K; Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania., Mickevicius A; Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania., Hollenbach M; Division of Gastroenterology, University of Leipzig Medical Center, Leipzig, Germany., Molcan P; Hepatology and Gastroenterology Department of Roosevelt Hospital, Banska Bystrica, Slovakia., Ioannidis O; 4th Department of Surgery, Medical School, Aristotle University of Thessaloniki, General Hospital 'George Papanikolaou', Thessaloniki, Greece., Tokarev MV; Sklifosovsky Institute for Clinical Medicine, Sechenov First Moscow State Medical University, Moscow, Russia., Ince AT; Hospital of Bezmialem Vakif University, School of Medicine, Istanbul, Turkey., Semenenko IA; Sechenov University, Moscow, Russia., Galeev S; Saint Luke Clinical Hospital, St. Petersburg, Russia., Ramírez-Maldonado E; General Surgery, Consorci Sanitari del Garraf, Sant Pere de Ribes, Barcelona, Spain., Sallinen V; Department of Transplantation and Liver Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Pencik P; Centrum péče o zažívací trakt, Vítkovická Nemocnice a.s., Ostrava, Czech Republic., Bajor J; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary., Sarlós P; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary., Hágendorn R; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary., Gódi S; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary., Szabó I; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary., Czimmer J; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary., Pár G; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary., Illés A; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Pécs, Hungary., Faluhelyi N; Department of Medical Imaging, Medical School, University of Pécs, Pécs, Hungary., Kanizsai P; Department of Emergency Medicine, Medical School, University of Pécs, Pécs, Hungary., Nagy T; Department of Laboratory Medicine, Medical School, University of Pécs, Pécs, Hungary., Mikó A; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary., Németh B; Department of Medicine, University of Szeged, Szeged, Hungary., Hamvas J; Peterfy Hospital, Budapest, Hungary., Bod B; Dr. Bugyi István Hospital, Szentes, Hungary., Varga M; Department of Gastroenterology, BMKK Dr Rethy Pal Hospital, Békéscsaba, Hungary., Török I; County Emergency Clinical Hospital of Târgu Mures - Gastroenterology Clinic and University of Medicine, Pharmacy, Sciences and Technology 'George Emil Palade', Targu Mures, Romania., Novák J; Pándy Kálmán Hospital of Békés County, Gyula, Hungary., Patai Á; Markusovszky University Teaching Hospital, Szombathely, Hungary., Sümegi J; Borsod-Abaúj-Zemplén County Hospital and University Teaching Hospital, Miskolc, Hungary., Góg C; Healthcare Center of County Csongrád, Makó, Hungary., Papp M; Department of Gastroenterology, Institute of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Erőss B; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Váncsa S; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary.; Department of Laboratory Medicine, Semmelweis University, Budapest, Hungary., Teutsch B; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.; Department of Laboratory Medicine, Semmelweis University, Budapest, Hungary., Márta K; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Hegyi PJ; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Tornai T; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Lázár B; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Hussein T; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Tarján D; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Lipp M; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Kovács B; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Urbán O; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Fürst E; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Tari E; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Kocsis I; Department of Laboratory Medicine, Semmelweis University, Budapest, Hungary., Maurovich-Horvát P; MTA-SE Cardiovascular Imaging Research Group, Medical Imaging Centre, Semmelweis University, Budapest, Hungary., Tihanyi B; Department for Surgery, Hungarian Defence Forces - Medical Centre, Budapest, Hungary., Eperjesi O; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Kormos Z; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary., Deák PÁ; Medical Imaging Centre, Department of Radiology, Semmelweis University, Budapest, Hungary., Párniczky A; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.; Heim Pál National Pediatric Institute, Budapest, Hungary., Hegyi P; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary. hegyi.peter@semmelweis.hu.; Institute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary. hegyi.peter@semmelweis.hu.; Institute of Pancreatic Diseases, Semmelweis University, Budapest, Hungary. hegyi.peter@semmelweis.hu.; Translational Pancreatology Research Group, Interdisciplinary Centre of Excellence for Research Development and Innovation, University of Szeged, Szeged, Hungary. hegyi.peter@semmelweis.hu. |
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Jazyk: | angličtina |
Zdroj: | Scientific reports [Sci Rep] 2023 Dec 13; Vol. 13 (1), pp. 22109. Date of Electronic Publication: 2023 Dec 13. |
DOI: | 10.1038/s41598-023-48480-z |
Abstrakt: | There are several overlapping clinical practice guidelines in acute pancreatitis (AP), however, none of them contains suggestions on patient discharge. The Hungarian Pancreatic Study Group (HPSG) has recently developed a laboratory data and symptom-based discharge protocol which needs to be validated. (1) A survey was conducted involving all members of the International Association of Pancreatology (IAP) to understand the characteristics of international discharge protocols. (2) We investigated the safety and effectiveness of the HPSG-discharge protocol. According to our international survey, 87.5% (49/56) of the centres had no discharge protocol. Patients discharged based on protocols have a significantly shorter median length of hospitalization (LOH) (7 (5;10) days vs. 8 (5;12) days) p < 0.001), and a lower rate of readmission due to recurrent AP episodes (p = 0.005). There was no difference in median discharge CRP level among the international cohorts (p = 0.586). HPSG-protocol resulted in the shortest LOH (6 (5;9) days) and highest median CRP (35.40 (13.78; 68.40) mg/l). Safety was confirmed by the low rate of readmittance (n = 35; 5%). Discharge protocol is necessary in AP. The discharge protocol used in this study is the first clinically proven protocol. Developing and testifying further protocols are needed to better standardize patients' care. (© 2023. The Author(s).) |
Databáze: | MEDLINE |
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