Predictive value of General Movements Assessment for developmental delay at 18 months in children with complex congenital heart disease.

Autor: Huisenga DC; Advocate Children's Hospital, Department of Pediatric Rehabilitation and Development, Oak Lawn, IL, USA; University of Groningen, University Medical Center Groningen, Department of Paediatrics, Division of Developmental Neurology, Groningen, the Netherlands., la Bastide-van Gemert S; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, the Netherlands., Van Bergen AH; Advocate Children's Hospital, Advocate Children's Heart Institute, Division of Pediatric Cardiac Critical Care, Oak Lawn, IL, USA., Sweeney JK; Rocky Mountain University of Health Professions, Provo, UT, USA., Hadders-Algra M; University of Groningen, University Medical Center Groningen, Department of Paediatrics, Division of Developmental Neurology, Groningen, the Netherlands. Electronic address: m.hadders-algra@umcg.nl.
Jazyk: angličtina
Zdroj: Early human development [Early Hum Dev] 2024 Jan; Vol. 188, pp. 105916. Date of Electronic Publication: 2023 Dec 08.
DOI: 10.1016/j.earlhumdev.2023.105916
Abstrakt: Background: Infants with complex congenital heart disease are at increased risk of impaired fetal brain growth, brain injury, and developmental impairments. The General Movement Assessment (GMA) is a valid and reliable tool to predict cerebral palsy (CP), especially in preterm infants. Predictive properties of the GMA in infants with complex congenital heart disease (CCHD) are unknown.
Aim: To evaluate predictive properties of the GMA to predict developmental outcomes, including cerebral palsy (CP), at 18-months corrected age (CA) in children with CCHD undergoing heart surgery in the first month of life.
Methods: A prospective cohort of 56 infants with CCHD (35 males, 21 females) was assessed with GMA at writhing age (0-6 weeks CA) and fidgety age (7-17 weeks CA) and the Bayley Scales of Infant Development at 18 months. GMA focused on markedly reduced GM-variation and complexity (definitely abnormal (DA) GM-complexity) and fidgety movements. Predictive values of GMA for specific cognitive, language and motor delay (composite scores <85th percentile) and general developmental delay (delay in all domains) were calculated at 18 months.
Results: At fidgety age, all infants had fidgety movements and no child was diagnosed with CP. DA GM-complexity at fidgety age predicted general developmental delay at 18 months (71 % sensitivity, 90 % specificity), but predicted specific developmental delay less robustly. DA GM-complexity at writhing age did not predict developmental delay, nor did it improve prediction based on DA GM-complexity at fidgety age.
Conclusions: In infants with CCHD and fidgety movements, DA GM-complexity at fidgety age predicted general developmental delay.
Competing Interests: Declaration of competing interest Mijna Hadders-Algra has provided courses on the GMA since 1993. She did not get an honorarium, grant, or other form of payment to produce this manuscript. The other authors declare no conflict of interest.
(Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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