Community-acquired pneumonia: Epidemiology, diagnosis, prognostic severity scales, and new therapeutic options.

Autor:	Oliveira E Silva PG; Research Department, Imed Group Brasil, São Paulo, Brazil., Cerqueira Batista Filho LA; Research Department, Imed Group Brasil, São Paulo, Brazil., Ismael PF; Research Department, Imed Group Brasil, São Paulo, Brazil., Victoria VES; Research Department, Imed Group Brasil, São Paulo, Brazil., Alexandre TM; Research Department, Imed Group Brasil, São Paulo, Brazil., Larissa SM; Research Department, Imed Group Brasil, São Paulo, Brazil.
Jazyk:	English; Spanish; Castilian
Zdroj:	Medwave [Medwave] 2023 Dec 07; Vol. 23 (11), pp. e2719. Date of Electronic Publication: 2023 Dec 07.
DOI:	10.5867/medwave.2023.11.2719
Abstrakt:	This narrative review article explores the current scientific knowledge on the definition, epidemiology, diagnostic criteria, microbiology, treatment, and prevention of severe community-acquired pneumonia (SCAP) in immunocompetent adults. At present, despite major scientific advances in diagnostic evaluation, clinical management, antimicrobial therapy, and prevention, severe community-acquired pneumonia remains a major cause of morbidity and mortality, as well as having a major economic impact in terms of increased healthcare expenditure worldwide. This pathology is considered one of the leading causes of sepsis/septic shock, with an extremely high overall mortality rate, which justifies all the effort in early diagnosis, proper management, and prompt initiation of antimicrobial therapy. Including biomarkers (isolated or in combination) associated with applying diagnostic criteria and prognostic severity scales in clinical practice helps identify patients with severe community-acquired pneumonia, defines immediate admission to the intensive care unit, and, thus, minimizes the adverse outcomes of this serious pathology. Competing Interests: The authors declare no conflicts of interest. (This work is licensed under a Creative Commons Attribution 4.0 International License.)
Databáze:	MEDLINE
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