Pediatric long-term noninvasive respiratory support in children with central nervous system disorders.

Autor: Carrara M; Department of Pediatric Pulmonology, AP-HP, Hôpital Armand Trousseau, Paris, France., Aubertin G; Department of Pediatric Pulmonology, AP-HP, Hôpital Armand Trousseau, Paris, France.; Sorbonne Université, INSERM UMR-S 938, Centre de Recherche Saint-Antoine (CRSA), Paris, France.; Centre de pneumologie de l'enfant, Ramsay Générale de Santé, Paris, France., Khirani S; Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker-Enfants malades, Paris, France.; Université Paris Cité, VIFASOM, Paris, France.; ASV Santé, Gennevilliers, France., Massenavette B; Pediatric Intensive Care Unit, Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Bron, France., Bierme P; Pediatric Pulmonology and Allergology Unit, Hospices Civils de Lyon, Bron, France., Griffon L; Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker-Enfants malades, Paris, France.; Université Paris Cité, VIFASOM, Paris, France., Ioan I; Department of Pediatric, University Children's Hospital, CHRU Nancy; Université de Lorraine, DevAH, Nancy, France., Schweitzer C; Department of Pediatric, University Children's Hospital, CHRU Nancy; Université de Lorraine, DevAH, Nancy, France., Binoche A; Pediatric Intensive Care Unit, Hôpital Jeanne de Flandre, CHU Lille, Lille, France., Lampin ME; Pediatric Intensive Care Unit, Hôpital Jeanne de Flandre, CHU Lille, Lille, France., Mordacq C; Pediatic Pulmonology and Allergology Unit, Hôpital Jeanne de Flandre, CHU Lille, Lille, France., Rubinsztajn R; Department of Pediatric orthopedic surgery, Hôpital Necker-Enfants malades, Paris, France., Debeilleix S; Pediatric Pulmonology Unit, Hôpital Pellegrin-Enfants, Bordeaux, France., Galode F; Pediatric Pulmonology Unit, Hôpital Pellegrin-Enfants, Bordeaux, France., Bui S; Pediatric Pulmonology Unit, Hôpital Pellegrin-Enfants, Bordeaux, France., Hullo E; Pediatric Pulmonology Unit, Hôpital Couple-Enfant, CHU Grenoble, Grenoble, France., Becourt A; Pediatric Pulmonology Department, CHU Amiens Picardie, Amiens, France., Lubrano M; Respiratory Diseases, Allergy and CF Unit, Department of Pediatric, University Hospital Charles Nicolle, Rouen, France., Moreau J; Department of Pediatric Cardiology and Pulmonology, Montpellier University Hospital, Montpellier, France.; Physiology and Experimental Biology of Heart and Muscles Laboratory-PHYMEDEXP, UMR CNRS 9214, INSERM U1046, University of Montpellier, Montpellier, France., Renoux MC; Department of Pediatric Cardiology and Pulmonology, Montpellier University Hospital, Montpellier, France., Matecki S; Department of Pediatric Cardiology and Pulmonology, Montpellier University Hospital, Montpellier, France.; Functional Exploration Laboratory, University Hospital, Montpellier, France., Stremler N; Pediatric Ventilation Unit, Department of Pediatric, AP-HM, Hôpital La Timone, Marseille, France., Baravalle-Einaudi M; Pediatric Ventilation Unit, Department of Pediatric, AP-HM, Hôpital La Timone, Marseille, France., Mazenq J; Pediatric Ventilation Unit, Department of Pediatric, AP-HM, Hôpital La Timone, Marseille, France., Sigur E; Pediatric Pulmonology and Allergology Unit, Hôpital des Enfants, Toulouse, France., Labouret G; Pediatric Pulmonology and Allergology Unit, Hôpital des Enfants, Toulouse, France., Genevois AL; Pediatric Pulmonology and Allergology Unit, Hôpital des Enfants, Toulouse, France., Heyman R; Pediatric Unit, Department of Physical Medicine and Rehabilitation, Hôpital Pontchaillou, Rennes, France., Pomedio M; Pediatric Intensive Care Unit, American Memorial Hospital, CHU Reims, Reims, France., Masson A; Pediatric Unit, Hôpital de la Mère et de l'Enfant, Limoges, France., Hangard P; Pediatric Unit, Hôpital de la Mère et de l'Enfant, Limoges, France., Menetrey C; Pediatric Unit, Hôpital de la Mère et de l'Enfant, Limoges, France., Le Clainche L; Pediatric Noninvasive Ventilation Unit, AP-HP, Hôpital Robert Debré, Paris, France., Bokov P; Pediatric Noninvasive Ventilation Unit, AP-HP, Hôpital Robert Debré, Paris, France.; Université Paris Cité, INSERM NeuroDiderot, Paris, France., Dudoignon B; Pediatric Noninvasive Ventilation Unit, AP-HP, Hôpital Robert Debré, Paris, France., Fleurence E; ESEAN-APF, Health Center for Children and Adolescents, Nantes, France., Bergounioux J; Pediatric Intensive Care Unit, AP-HP, Hôpital Raymond Poincaré, Garches, France., Mbieleu B; Pediatric Intensive Care Unit, AP-HP, Hôpital Raymond Poincaré, Garches, France., Breining A; Department of Pediatric, CHU Strasbourg, Strasbourg, France., Giovannin-Chami L; Department of Pediatric Pulmonology and Allergology, Hôpitaux pédiatriques de Nice CHU-Lenval, Nice, France., Fina A; Department of Pediatric Pulmonology and Allergology, Hôpitaux pédiatriques de Nice CHU-Lenval, Nice, France., Ollivier M; Pediatric Intensive Care Unit, CHU Angers, Angers, France., Gachelin E; Department of Pediatric, CHU Félix Guyon, Saint Denis, La Réunion, France., Perisson C; Department of Pediatric, CHU Sud Réunion, Saint Pierre, La Réunion, France., Pervillé A; Department of Pédiatrics, Hôpital d'Enfants-ASFA, Saint Denis, La Réunion, France., Barzic A; Department of Pediatric, CHU Brest, Brest, France., Cros P; Department of Pediatric, CHU Brest, Brest, France., Jokic M; Pediatric Intensive Care Unit, CHU de Caen Normandie, Caen, France., Labbé G; Pediatric Pulmonology and Allergology Unit, CHU d'Estaing, Clermont-Ferrand, France., Diaz V; Department of Respiratory Physiology, CHU Poitiers, Poitiers, France., Coutier L; Pediatric Pulmonology and Allergology Unit, Hospices Civils de Lyon, Bron, France., Fauroux B; Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker-Enfants malades, Paris, France.; Université Paris Cité, VIFASOM, Paris, France., Taytard J; Department of Pediatric Pulmonology, AP-HP, Hôpital Armand Trousseau, Paris, France.; INSERM UMR-S 1158 'Neurophysiologie Respiratoire Expérimentale et Clinique', Sorbonne Université, Paris, France, Paris, France.
Jazyk: angličtina
Zdroj: Pediatric pulmonology [Pediatr Pulmonol] 2024 Mar; Vol. 59 (3), pp. 642-651. Date of Electronic Publication: 2023 Dec 13.
DOI: 10.1002/ppul.26796
Abstrakt: Rationale: The use of long-term noninvasive respiratory support is increasing in children along with an extension of indications, in particular in children with central nervous system (CNS) disorders.
Objective: The aim of this study was to describe the characteristics of children with CNS disorders treated with long-term noninvasive respiratory support in France.
Methods: Data were collected from 27 French pediatric university centers through an anonymous questionnaire filled for every child treated with noninvasive ventilatory support ≥3 months on 1st June 2019.
Main Results: The data of 182 patients (55% boys, median age: 10.2 [5.4;14.8] years old [range: 0.3-25]) were collected: 35 (19%) patients had nontumoral spinal cord injury, 22 (12%) CNS tumors, 63 (35%) multiple disabilities, 26 (14%) central alveolar hypoventilation and 36 (20%) other CNS disorders. Seventy five percent of the patients were treated with noninvasive ventilation (NIV) and 25% with continuous positive airway pressure (CPAP). The main investigations performed before CPAP/NIV initiation were nocturnal gas exchange recordings, alone or coupled with poly(somno)graphy (in 29% and 34% of the patients, respectively). CPAP/NIV was started in an acute setting in 10% of the patients. Median adherence was 8 [6;10] hours/night, with 12% of patients using treatment <4 h/day. Nasal mask was the most common interface (70%). Airway clearance techniques were used by 31% of patients.
Conclusion: CPAP/NIV may be a therapeutic option in children with CNS disorders. Future studies should assess treatment efficacy and patient reported outcome measures.
(© 2023 Wiley Periodicals LLC.)
Databáze: MEDLINE
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