Differential contribution of language and executive functioning to verbal fluency performance in glioma patients.
Autor: | Collée E; Department of Neurosurgery, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands., van den Berg E; Department of Neurology and Alzheimer Center Erasmus MC, Erasmus MC - University Medical Center, Rotterdam, The Netherlands., Visch-Brink E; Department of Neurosurgery, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands., Vincent A; Department of Neurosurgery, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands., Dirven C; Department of Neurosurgery, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands., Satoer D; Department of Neurosurgery, Erasmus MC - University Medical Centre, Rotterdam, The Netherlands. |
---|---|
Jazyk: | angličtina |
Zdroj: | Journal of neuropsychology [J Neuropsychol] 2024 Mar; Vol. 18 Suppl 1, pp. 19-40. Date of Electronic Publication: 2023 Dec 12. |
DOI: | 10.1111/jnp.12356 |
Abstrakt: | Glioma patients often suffer from deficits in language and executive functioning. Performance in verbal fluency (generating words within one minute according to a semantic category-category fluency, or given letter-letter fluency) is typically impaired in this patient group. While both language and executive functioning play a role in verbal fluency, the relative contribution of both domains remains unclear. We aim to retrospectively investigate glioma patients' performance on verbal and nonverbal fluency and to explore the influence of language and executive functioning on verbal fluency. Sixty-nine adults with gliomas in eloquent areas underwent a neuropsychological test battery (verbal fluency, nonverbal fluency, language, and executive functioning tests) before surgery (T1) and a subgroup of 31 patients also at three (T2) and twelve months (T3) after surgery. Preoperatively, patients were impaired in all verbal fluency tasks and dissociations were found based on tumour location. In contrast, nonverbal fluency was intact. Different language and executive functioning tests predicted performance on category fluency animals and letter fluency, while no significant predictors for category fluency professions were found. The longitudinal results indicated that category fluency professions deteriorated after surgery (T1-T2, T1-T3) and that nonverbal fluency improved after surgery (T1-T3, T2-T3). Verbal fluency performance can provide information on different possible underlying deficits in language and executive functioning in glioma patients, depending on verbal fluency task selection. Efficient task (order) selection can be based on complexity. Category fluency professions can be selected to detect more permanent long-term deficits. (© 2023 The Authors. Journal of Neuropsychology published by John Wiley & Sons Ltd on behalf of The British Psychological Society.) |
Databáze: | MEDLINE |
Externí odkaz: |