A potential approach toward the management of sepsis: The extracorporeal cytokine hemadsorption therapy.

Autor: Yildiz AB; School of Medicine, Koc University, Istanbul, Turkey., Copur S; Department of Internal Medicine, School of Medicine, Koc University, Istanbul, Turkey., Tanriover C; School of Medicine, Koc University, Istanbul, Turkey., Yavuz F; School of Medicine, Koc University, Istanbul, Turkey., Vehbi S; School of Medicine, Koc University, Istanbul, Turkey., Hasbal NB; Division of Nephrology, Department of Internal Medicine, School of Medicine, Koc University, Istanbul, Turkey., Kanbay M; Division of Nephrology, Department of Internal Medicine, School of Medicine, Koc University, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Seminars in dialysis [Semin Dial] 2024 Mar-Apr; Vol. 37 (2), pp. 117-121. Date of Electronic Publication: 2023 Dec 12.
DOI: 10.1111/sdi.13188
Abstrakt: Infectious diseases are among the most common cause of morbidity and mortality among hospitalized patients while systemic inflammatory response syndrome is primarily attributed to the imbalance between pro-inflammatory and anti-inflammatory cytokines. Despite the improvements in the antibiotherapy alternatives and diagnostic modalities, the morbidity and mortality rates of sepsis and septic shock are relatively high among patients admitted to the intensive care units. Extracorporeal cytokine hemadsorption therapies are therapeutic approaches for such patient group with promising early results that especially have grown during COVID-19 pandemic. In this narrative review, our aim is to evaluate the current pre-clinical and clinical knowledge regarding the use of cytokine filtration systems among patients with septic shock.
(© 2023 Wiley Periodicals LLC.)
Databáze: MEDLINE
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