Modeling clinical malaria episodes in different ecological settings in Mali, 2018-2022.

Autor:	Kane F; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Toure M; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Sogoba N; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; Malaria Research and Training Center (MRTC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Traore B; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; Malaria Research and Training Center (MRTC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Keita M; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; Malaria Research and Training Center (MRTC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Konate D; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Diawara SI; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Sanogo D; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Keita S; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Sanogo I; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Doumbia CO; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Keïta B; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; Malaria Research and Training Center (MRTC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Traoré AS; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Sissoko I; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; Malaria Research and Training Center (MRTC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Coulibaly H; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Thiam SM; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Barry A; Institute for Mental and Physical Health and Clinical Translation (IMPACT) and School of Medicine, Deakin University, Geelong, Australia., Shaffer JG; School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana., Diakite M; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Doumbia S; West African International Center for Excellence in Malaria Research, Techniques and Technologies of Bamako, Bamako, Mali.; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali.
Jazyk:	angličtina
Zdroj:	IJID regions [IJID Reg] 2023 Nov 11; Vol. 10, pp. 24-30. Date of Electronic Publication: 2023 Nov 11 (Print Publication: 2024).
DOI:	10.1016/j.ijregi.2023.11.006
Abstrakt:	Objectives: Following the scaling-up of malaria control strategies in Mali, understanding the changes in age-specific prevalence of infection and risk factors associated with remains necessary to determine new priorities to progress toward disease elimination. This study aimed to estimate the risk of clinical malaria using longitudinal data across three different transmission settings in Mali. Methods: Cohort-based longitudinal studies were performed from April 2018 to December 2022. Incidence of malaria was measured through community health center-based passive case detection. Generalized estimation equation model was used to assess risk factors for clinical malaria. Results: A total of 21,453 clinical presentations were reported from 4500 participants, mainly from July to November. Data shows a significant association between malaria episodes, sex, age group, season, and year. Women had lower risk, the risk of clinical episode increased with age up to 14 years then declined, and in both sites, the dry-season risk of clinical episode was significantly lower compared to the rainy season. Conclusion: Determining factors associated with the occurrence of clinical malaria across different ecological settings across the country could help in the development of new strategies aiming to accelerate malaria elimination in an area where malaria transmission remains intense. Competing Interests: The authors have no competing interests to declare. (© 2023 The Authors.)
Databáze:	MEDLINE
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