Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experience.

Autor:	Rahhal A; Pharmacy Department, Hamad Medical Corporation, Doha, Qatar., Najim M; Internal Medicine Department, Rochester Regional Health - Unity Hospital, New York, USA., Mahfouz A; Pharmacy Department, Hamad Medical Corporation, Doha, Qatar., Habib MB; Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar., Hassen SS; Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar., Al-Shekh I; Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar., Ahmed AO; Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar., Toba H; Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar., Abbarh S; Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar., El Hassan M; Critical Care Department, Hamad Medical Corporation, Doha, Qatar., Al Yafei S; Pharmacy Department, Hamad Medical Corporation, Doha, Qatar., Badr A; Heart Failure Department, Hamad Medical Corporation, Doha, Qatar., Mahmoud KM; Nephology Department, Hamad Medical Corporation, Doha, Qatar.; Urology and Nephrology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Jazyk:	angličtina
Zdroj:	Open medicine (Warsaw, Poland) [Open Med (Wars)] 2023 Dec 06; Vol. 18 (1), pp. 20230868. Date of Electronic Publication: 2023 Dec 06 (Print Publication: 2023).
DOI:	10.1515/med-2023-0868
Abstrakt:	Sustained low-efficiency dialysis (SLED) is usually performed over 6-12 h among hemodynamically unstable patients. Conduction of 4-h SLED may spare time and manpower during hospitalization. Therefore, we conducted a retrospective observational study to explore the appropriateness and clinical outcomes of 4-h SLED among critically ill patients admitted to our center from 1/06/2016 to 1/06/2020. Renal parameters including blood urea nitrogen, serum creatinine, sodium, phosphorus, potassium, and bicarbonate were determined on the day of dialysis before SLED and within 24 h after SLED, and clinical outcomes including, acute kidney injury (AKI) recovery, in-hospital mortality, 30-day mortality, 180-day mortality, and re-admission with AKI, were evaluated. Of the 304 patients included, 69.4% were male. The majority of patients were from the Middle East (65.8%), followed by 28.6% from Asia. Four-hour SLED resulted in a significant improvement in the renal parameters. Recovery from AKI was observed in 25.4%, in-hospital mortality rate was 48.7%, while the 30- and 180-day mortality outcomes were 3.2 and 9.6%, respectively, and re-admission with AKI was observed in 16.9%. Our findings suggest that 4-h SLED significantly improved renal parameters and was associated with favorable clinical outcomes in terms of survival and AKI recovery, suggesting possible utilization of SLED shorter than 6 h in the acute settings to preserve time and manpower for procedures. Competing Interests: Conflict of interest: The authors declare that they have no conflict of interest. (© 2023 the author(s), published by De Gruyter.)
Databáze:	MEDLINE
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