Acute pancreatitis related to hypercalcemia as initial manifestation of cancer: About 4 cases.

Autor: Amri F; Department of Hepato-Gastroenterology, Mohammed VI University Hospital, Oujda, Morocco.; Digestive Diseases Research Laboratory (DSRL), Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco., Bensalah Y; Department of Hepato-Gastroenterology, Mohammed VI University Hospital, Oujda, Morocco.; Digestive Diseases Research Laboratory (DSRL), Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco., Zazour A; Department of Hepato-Gastroenterology, Mohammed VI University Hospital, Oujda, Morocco.; Digestive Diseases Research Laboratory (DSRL), Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco., Aggari HE; Department of Radiology, Mohammed VI University Hospital, Oujda, Morocco., Koulali H; Department of Hepato-Gastroenterology, Mohammed VI University Hospital, Oujda, Morocco.; Digestive Diseases Research Laboratory (DSRL), Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco., Mqaddem OE; Department of Hepato-Gastroenterology, Mohammed VI University Hospital, Oujda, Morocco.; Digestive Diseases Research Laboratory (DSRL), Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco., Skiker I; Department of Radiology, Mohammed VI University Hospital, Oujda, Morocco., Ismaili Z; Department of Hepato-Gastroenterology, Mohammed VI University Hospital, Oujda, Morocco.; Digestive Diseases Research Laboratory (DSRL), Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco., Kharrasse G; Department of Hepato-Gastroenterology, Mohammed VI University Hospital, Oujda, Morocco.; Digestive Diseases Research Laboratory (DSRL), Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco.
Jazyk: angličtina
Zdroj: Radiology case reports [Radiol Case Rep] 2023 Dec 03; Vol. 19 (2), pp. 753-759. Date of Electronic Publication: 2023 Dec 03 (Print Publication: 2024).
DOI: 10.1016/j.radcr.2023.11.017
Abstrakt: Acute pancreatitis is a frequent gastrointestinal emergency seen in tertiary care hospitals. While gallstones and chronic alcohol consumption remain the most common causes, other etiologies can also be identified, notably hypercalcemia, which constitutes a rare yet deadly cause of acute pancreatitis. Herein, we report 4 cases of AP related to hypercalcemia from malignancies: 2 cases of multiple myeloma, one case of rectal malignancy, and 1 case of medullary thyroid carcinoma associated with a parathyroid adenoma. Among these cases, one patient died, one developed exocrine and endocrine pancreatic insufficiency, and another progressed to end-stage chronic renal failure. Awareness of hypercalcemia of malignancy as an exceptional etiology of AP is crucial for timely diagnosis and appropriate management of these cases.
(© 2023 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)
Databáze: MEDLINE