Classic Light Transmission Platelet Aggregometry: Do We Still Need it?
| Autor: | Gebetsberger J; Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria., Prüller F; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria. |
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| Jazyk: | angličtina |
| Zdroj: | Hamostaseologie [Hamostaseologie] 2024 Aug; Vol. 44 (4), pp. 304-315. Date of Electronic Publication: 2023 Dec 08. |
| DOI: | 10.1055/a-2117-4614 |
| Abstrakt: | For more than 50 years, light transmission aggregometry has been accepted as the gold standard test for diagnosing inherited platelet disorders in platelet-rich plasma, although there are other functional approaches performed in whole blood. In this article, several advantages and disadvantages of this technique over other laboratory approaches are discussed in the view of recent guidelines, and the necessity of functional assays, such as light transmission aggregometry in the era of molecular genetic testing, is highlighted. Competing Interests: The authors declare that they have no conflict of interest. (Thieme. All rights reserved.) |
| Databáze: | MEDLINE |
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