Cellular dormancy: A widespread phenomenon that perpetuates infectious diseases.

Autor: da Silva CV; Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Brazil., Velikkakam T; Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Brazil., de Oliveira ECM; Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Brazil., Silveira ACA; Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Brazil., de Lima Júnior JP; Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Brazil., Uombe NPI; Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Brazil., da Silva PHR; Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Brazil., Borges BC; Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Uberlândia, Brazil.
Jazyk: angličtina
Zdroj: Journal of basic microbiology [J Basic Microbiol] 2024 May; Vol. 64 (5), pp. e2300389. Date of Electronic Publication: 2023 Dec 08.
DOI: 10.1002/jobm.202300389
Abstrakt: Under adverse environmental conditions, microorganisms are able to enter a state of cellular dormancy which consists of cell cycle arrest and interruption of multiplication. This process ensures their perpetuation in the infected host organism and enables the spread of disease. Throughout biological evolution, dormancy allowed microorganisms to persist in a harsh niche until favorable conditions for their reactivation were re-established. Here, we propose to discuss the dormancy of bacteria and protozoa pathogens focusing on the potential mechanisms and components associated with dormancy.
(© 2023 Wiley‐VCH GmbH.)
Databáze: MEDLINE
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