Long-term surgical outcomes of pediatric cataract-multivariate analysis of prognostic factors.

Autor: Oshika T; Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8575, Japan. oshika@eye.ac., Endo T; Osaka Women's and Children's Hospital, Osaka, Japan., Kurosaka D; Department of Ophthalmology, Iwate Medical University School of Medicine, Iwate, Japan., Matsuki N; Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan., Miyagi M; Aichi Children's Health and Medical Center, Aichi, Japan., Mori T; Department of Ophthalmology, Fukushima Medical University, Fukushima, Japan., Nagamoto T; Nagamoto Eye Clinic, Tokyo, Japan., Negishi K; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan., Nishina S; National Center for Child Health and Development, Tokyo, Japan., Nomura K; Hyogo Prefectural Kobe Children's Hospital, Hyogo, Japan., Unoki N; Osaka City General Hospital, Osaka, Japan., Yoshida S; Department of Ophthalmology, Kurume University School of Medicine, Fukuoka, Japan.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 Dec 08; Vol. 13 (1), pp. 21645. Date of Electronic Publication: 2023 Dec 08.
DOI: 10.1038/s41598-023-49166-2
Abstrakt: We assessed the 10-year postoperative outcomes of pediatric cataract patients who underwent surgery at the age of 6 years or younger. A retrospective review of medical charts was conducted for 457 eyes of 277 patients, with the age at surgery averaging 1.3 ± 1.5 years (mean ± SD) and the follow-up duration averaging 12.8 ± 2.4 years (ranging from 10 to 17 years). The cohort included 250 eyes of 125 cases with bilateral aphakia (age at surgery 0.5 ± 0.8 years), 110 eyes of 55 cases with bilateral pseudophakia (1.9 ± 1.6 years), 42 cases with unilateral aphakia (1.1 ± 1.3 years), and 55 cases with unilateral pseudophakia (2.6 ± 1.7). A forward stepwise multiple regression analysis revealed that the best-corrected visual acuity at the final visit was significantly associated with laterality of cataract (with bilateral cases showing better results compared to unilateral cases), presence of systemic comorbidities, presence of ocular comorbidities, development of glaucoma, and phakic status (with better results in the pseudophakia group than the aphakia group). The age at surgery did not significantly affect visual acuity outcomes. A multiple logistic regression analysis demonstrated that the incidence of secondary glaucoma was significantly linked to younger age at surgery, phakic status (higher in aphakic than pseudophakic eyes), and presence of systemic comorbidities. In conclusion, after pediatric cataract surgery, final visual acuity was better in patients with bilateral cataracts, those treated with an intraocular lens, and cases without systemic or ocular comorbidities and secondary glaucoma. The development of secondary glaucoma was linked to younger age at surgery, aphakic status, and presence of systemic comorbidities.
(© 2023. The Author(s).)
Databáze: MEDLINE
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