Carcinoid heart disease: a potentially fatal complication of carcinoid syndrome.

Autor: Bdiwi M; Department of Internal Medicine, Wayne State University/ Detroit Medical Center, Detroit, Michigan, USA mbdiwi@med.wayne.edu., Ramaseshan K; Department of Internal Medicine, Wayne State University/ Detroit Medical Center, Detroit, Michigan, USA., Uddin M; Cardiology/Department of Internal medicine, Wayne State University/ Detroit Medical Center, Detroit, Michigan, USA., Goel M; Cardiology/Department of Internal medicine, Wayne State University/ Detroit Medical Center, Detroit, Michigan, USA., Razzaq S; Department of Internal Medicine, Wayne State University/ Detroit Medical Center, Detroit, Michigan, USA., Alrayyashi M; Department of Internal Medicine, Wayne State University/ Detroit Medical Center, Detroit, Michigan, USA., Afonso L; Cardiology/Department of Internal medicine, Wayne State University/ Detroit Medical Center, Detroit, Michigan, USA.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2023 Dec 06; Vol. 16 (12). Date of Electronic Publication: 2023 Dec 06.
DOI: 10.1136/bcr-2023-255518
Abstrakt: Carcinoid heart disease is a unique and serious cardiac complication of the neuroendocrine tumour that affects the right side of the heart, especially the tricuspid and pulmonic valves, eventually causing right heart failure. We present a middle-aged man with a history of well-differentiated neuroendocrine tumours of the small intestine with extensive metastases to the liver, mesentery and spine who is receiving monthly octreotide therapy. He presented with generalised fatigue, severe ascites and worsening dyspnoea. Both the transthoracic echocardiography and transoesophageal echocardiography revealed severe tricuspid and pulmonic regurgitations. He was considered a poor surgical candidate, underwent transcatheter pulmonic valve replacement with two bioprosthetic valve-in-valve implantations and was discharged in a stable condition.
Competing Interests: Competing interests: None declared.
(© BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE