Dietary effects of microalga Tetraselmis suecica on growth, antioxidant-immune activity, inflammation cytokines, and resistance of Nile tilapia fingerlings to Aeromonas sobria infection.

Autor: Abdel-Tawwab M; Department of Fish Biology and Ecology, Central Laboratory for Aquaculture Research, Agricultural Research Center, Abbassa, Abo-Hammad, Sharqia, Egypt., Khalil RH; Department of Poultry and Fish Diseases, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt., Abdel-Razek N; Department of Fish Health and Management, Central Laboratory for Aquaculture Research, Agricultural Research Center, Abbassa, Abo-Hammad, Sharqia, Egypt., Younis NA; Department of Aquatic Animal Medicine and Management, Faculty of Veterinary Medicine, Cairo University, Cairo, Egypt., Shady SHH; Department of Fish Biology and Ecology, Central Laboratory for Aquaculture Research, Agricultural Research Center, Abbassa, Abo-Hammad, Sharqia, Egypt., Monier MN; Department of Fish Biology and Ecology, Central Laboratory for Aquaculture Research, Agricultural Research Center, Abbassa, Abo-Hammad, Sharqia, Egypt., Abdel-Latif HMR; Department of Poultry and Fish Diseases, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.
Jazyk: angličtina
Zdroj: Journal of animal physiology and animal nutrition [J Anim Physiol Anim Nutr (Berl)] 2024 Mar; Vol. 108 (2), pp. 511-526. Date of Electronic Publication: 2023 Dec 06.
DOI: 10.1111/jpn.13911
Abstrakt: The dietary effects of the green microalga Tetraselmis suecica (TS) on the growth, digestive enzymes, immune and antioxidant responses, genes expression, and disease resistance of Nile tilapia (Oreochromis niloticus) fingerlings were investigated. This microalga was mixed with the diet' ingredients at doses of 0.0 (the control), 5, 10, 15, and 20 g/kg diet and then fed to fish daily for 84 days. After the feeding trial, fish were experimentally challenged with Aeromonas sobria, infection and fish mortalities were recorded for another 10 days. Dietary TS significantly (p < 0.05) enhanced growth, digestive enzymes activities, and blood proteins, particularly at the level of 15 g/kg diet. Feeding the fish on 15 TS/kg feed exhibited highest mRNA expressions of GH and IGF-1 genes as well as SOD, CAT, and GPx genes compared to other TS groups. Moreover, highest levels of hepatic antioxidant and immune indices were found in the treatment of 15 g TS/kg feed. Significant downregulation of IL-1β and IL-8 genes expression and significant upregulation of IL-10 gene expression were observed in TS-fed fish, principally in fish groups fed on 15-20 g TS/kg feed. Conversely, hepatic malondialdehyde levels, blood glucose, and the activities of transaminases (ALT and AST) were significantly (p < 0.05) decreased in fish fed with 15-20 g TS/kg diet. Serum bactericidal activity against A. sobria was significantly higher in TS-fed fish groups, and its highest levels were found in treatments of 15-20 g/kg diet. Of interest, the survival rates of fish groups fed diets with 10-20 g TS/kg feed were higher after the challenge with A. sobria infection than the control group. Accordingly, we can conclude that supplementing fish diets with a 15 g TS/kg diet enhanced the growth, antioxidant and immune activities, and resistance of Nile tilapia fingerlings to possible A. sobria infection.
(© 2023 Wiley-VCH GmbH. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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