Assessing the osseointegration potential of a strontium releasing nanostructured titanium oxide surface: A biomechanical study in the rabbit tibia plateau model.

Autor: Isler SC; Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.; Department of Periodontology, Faculty of Dentistry, Gazi University, Ankara, Turkey., Bellon B; Preclinical & Translational Research, Institut Straumann AG, Basel, Switzerland.; Department of Periodontology, Faculty of Dentistry, University of Zurich, Zurich, Switzerland., Foss M; iNANO and Department of Physics and Astronomy, Science and Technology, Aarhus, Denmark., Pippenger B; Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.; Preclinical & Translational Research, Institut Straumann AG, Basel, Switzerland., Stavropoulos A; Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.; Department of Periodontology, Faculty of Odontology, Malmö University, Malmö, Sweden.; Division of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, Vienna, Austria., Andersen OZ; Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.; Preclinical & Translational Research, Institut Straumann AG, Basel, Switzerland.
Jazyk: angličtina
Zdroj: Clinical and experimental dental research [Clin Exp Dent Res] 2024 Feb; Vol. 10 (1), pp. e812. Date of Electronic Publication: 2023 Dec 03.
DOI: 10.1002/cre2.812
Abstrakt: Objectives: To investigate the impact of a Ti-Sr-O technology, applied to either a turned surface or an SLA surface, on the mechanical robustness of osseointegration, benchmarked against the SLActive surface.
Material and Methods: Ti discs (6.25-mm-diameter and 2-mm-thick) with three different surfaces were inserted on the proximal-anterior part of the tibial plateau of adult Swedish loop rabbits: (I) turned surface modified with Ti-Sr-O (turned + Ti-Sr-O), (II) SLA surface modified with Ti-Sr-O (SLA + Ti-Sr-O), and (III) SLActive surface (SLActive). Following a healing period of 2 weeks and 4 weeks, the pull-out (PO) force needed to detach the discs from the bone was assessed, as a surrogate of osseointegration.
Results: The SLActive surface exhibited statistically significant higher median PO forces, compared with the SLA + Ti-Sr-O surfaces at both 2- and 4 weeks post-op (p > .05). In this study, no single turned + Ti-Sr-O surface disk was integrated.
Conclusions: The tested Ti-Sr-O technology failed to enhance osseointegration; however, this finding may be related to the inappropriateness of the rabbit tibia plateau model for assessing third-generation implant surface technologies, due to the limited diffusion and clearance at the disk-bone interface.
(© 2023 The Authors. Clinical and Experimental Dental Research published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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