Bacterial biofilm formation and anti-biofilm strategies.

Autor: Aransiola SA; Department of Microbiology, Faculty of Science, University of Abuja, PMB 117, Abuja, Nigeria., Selvaraj B; School of Chemical Engineering, Yeungnam University, Gyeongsan, Republic of Korea., Maddela NR; Departamento de Ciencias Biológicas, Facultad de Ciencias de la Salud, Universidad Técnica de Manabí, Portoviejo, Ecuador. Electronic address: raju.maddela@utm.edu.ec.
Jazyk: angličtina
Zdroj: Research in microbiology [Res Microbiol] 2024 Mar-Apr; Vol. 175 (3), pp. 104172. Date of Electronic Publication: 2023 Dec 02.
DOI: 10.1016/j.resmic.2023.104172
Abstrakt: Bacteria are ubiquitous prokaryotes. They are involved in biofilm formation and also have the ability to produce anti-biofilm products for biofilm mitigation. This special issue entitled: "Biofilms- community structure, applications and mitigation" of the journal Research in Microbiology was designed to discuss the flexibility of bacterial biofilms and their products under particular circumstances. Given that quorum sensing (QS) controls biofilm growth in some situations, especially for pathogenic bacteria antibiotic evading strategies. In Gram-negative bacteria, N-acyl homoserine lactones are the major quorum sensing signaling molecules. Another approach to prevent bacterial biofilm formation may be to inhibit the QS-regulated activities using quorum quenching (QQ). In this context, QS inhibitors and QS enzymes are important because they, respectively, interfere with signal creation, perception, or degradation and chemical modification. There have been numerous reports of QQ enzymes from bacteria. Treatment failure and recurrent staphylococcal infections are also brought on by biofilm development, which boosts an organism's ability to withstand antibiotics and is thought to be a virulence factor in patients. However, polyphenol quercetin antibiofilm activity is naturally available against drug-resistant Staphylococcus aureus.
(Copyright © 2023 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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