Prognostic value of stress hyperglycemia ratio in patients with acute myocardial infarction: A systematic review with Bayesian and frequentist meta-analysis.

Autor: Karakasis P; Second Department of Cardiology, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: pakar15@hotmail.com., Stalikas N; First Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece., Patoulias D; Outpatient Department of Cardiometabolic Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Greece; Second Department of Internal Medicine, European Interbalkan Medical Center, Thessaloniki, Greece., Pamporis K; Department of Hygiene, Social-Preventive Medicine & Medical Statistics, Medical School, Aristotle University of Thessaloniki, Greece., Karagiannidis E; Second Department of Cardiology, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Sagris M; First Department of Cardiology, Hippokration General Hospital, National and Kapodistrian University of Athens, Greece., Stachteas P; Second Department of Cardiology, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Bougioukas KI; Department of Hygiene, Social-Preventive Medicine & Medical Statistics, Medical School, Aristotle University of Thessaloniki, Greece., Anastasiou V; First Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece., Daios S; First Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece., Apostolidou-Kiouti F; Department of Hygiene, Social-Preventive Medicine & Medical Statistics, Medical School, Aristotle University of Thessaloniki, Greece., Giannakoulas G; First Department of Cardiology, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece., Vassilikos V; Third Department of Cardiology, Hippokration General Hospital, Aristotle University of Thessaloniki, Greece., Fragakis N; Second Department of Cardiology, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece., Giannopoulos G; Third Department of Cardiology, Hippokration General Hospital, Aristotle University of Thessaloniki, Greece.
Jazyk: angličtina
Zdroj: Trends in cardiovascular medicine [Trends Cardiovasc Med] 2024 Oct; Vol. 34 (7), pp. 453-465. Date of Electronic Publication: 2023 Nov 30.
DOI: 10.1016/j.tcm.2023.11.006
Abstrakt: The present systematic review and meta-analysis aimed to investigate the prognostic value of stress hyperglycemia ratio (SHR) in patients with acute myocardial infarction (AMI). A total of 26 cohort studies, involving 87,974 patients, were analyzed. The frequentist meta-analysis showed that AMI patients with SHR in the upper quantile had a significantly higher hazard of major adverse cardiovascular and cerebrovascular events (MACCE, HR = 1.7; 95 % CI= [1.42, 2.03]; P < 0.001; I 2 = 71 %; P <0.01), long-term (HR = 1.64; 95 % CI= [1.49, 1.8]; P < 0.001; I 2 = 16 %; P = 0.29) and in-hospital all-cause mortality (OR = 3.87; 95 % CI= [2.98, 5.03]; P < 0.001; I 2 = 54 %; P = 0.03) compared to those with lower SHR. Prespecified subgroup analyses revealed that these results were consistent irrespective of diabetes status (P = 0.32 and 0.73 for subgroup differences) and that SHR was a significant predictor of MACCE both in AMI with obstructive coronary arteries (HR = 1.57; 95 % CI= [1.34, 1.83]; P < 0.001; I 2 = 66 %; P < 0.01) and MINOCA (HR = 2.57; 95 % CI= [1.86, 3.56]; P < 0.001; I 2 = 0 %; P = 0.84). The Bayesian analyses with weakly prior assumptions yielded comparable results with the frequentist approach and provided strong evidence that higher SHR values were associated with significantly greater hazard of MACCE, short-term and long-term mortality. Further, prospective research is warranted to provide deeper insights into this newer index of stress hyperglycemia before its potential incorporation in clinical prediction scores.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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