Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study.

Autor: Adejumo OA; Department of Internal Medicine, University of Medical Sciences, Ondo City, Nigeria oaadejumo@unimed.edu.ng., Edeki IR; Department of Internal Medicine, University of Benin Teaching Hospital, Benin City, Nigeria., Mamven M; Department of Internal Medicine, University of Abuja, Abuja, Nigeria., Oguntola OS; Department of Internal Medicine, Afe Babalola University, Ado Ekiti, Nigeria., Okoye OC; Department of Internal Medicine, Delta State University, Abraka, Nigeria.; School of Health and Social Care, Edinburgh Napier University, Edinburgh, UK., Akinbodewa AA; Department of Internal Medicine, University of Medical Sciences, Ondo City, Nigeria., Okaka EI; Department of Internal Medicine, University of Benin, Benin City, Nigeria., Ahmed SD; Department of Internal Medicine, Irrua Specialist Teaching Hospital, Irrua, Nigeria., Egbi OG; Department of Internal Medicine, Niger Delta University, Okolobiri, Nigeria., Falade J; Department of Internal Medicine, University of Medical Sciences, Ondo City, Nigeria., Dada SA; Department of Internal Medicine, Ekiti State University, Ado Ekiti, Nigeria., Ogiator MO; Department of Internal Medicine, Benue State University, Makurdi, Nigeria., Okoh B; Department of Internal Medicine, Irrua Specialist Teaching Hospital, Irrua, Nigeria.
Jazyk: angličtina
Zdroj: BMJ open [BMJ Open] 2023 Dec 01; Vol. 13 (12), pp. e074025. Date of Electronic Publication: 2023 Dec 01.
DOI: 10.1136/bmjopen-2023-074025
Abstrakt: Objective: Poor sleep quality adversely affects the overall well-being and outcomes of patients with chronic kidney disease (CKD). However, it has not been well studied in Africans with CKD. We determined the prevalence of poor sleep quality and associated factors among patients with CKD.
Design: This was a cross-sectional study that involved patients with CKD .
Settings: The study was carried out in the outpatient clinic of nine hospitals in Nigeria.
Methods: Sleep quality, depressive and anxiety symptoms and quality of life (QoL) were assessed among 307 patients with CKD using Pittsburgh Sleep Quality Index Questionnaire, Hospital Anxiety Depression Scale Questionnaire and 12-item Short Form Health Survey Quality of Life Questionnaire, respectively. The prevalence of poor sleep quality and associated factors were determined. A p<0.05 was considered as statistically significant.
Results: The mean age of the study participants was 51.40±15.17 years. The male:female ratio was 1.5:1 One hundred and twenty-one (39.4%) of the patients were on maintenance haemodialysis (MHD). The prevalence of poor sleep quality, anxiety symptoms and depressive symptoms among the patients was 50.2%, 37.8% and 17.6%, respectively. The prevalence of poor sleep quality in the CKD stages 3, 4, 5 and 5D was 38.1%, 42.6%, 52.2% and 58.7%, respectively. The prevalence of poor sleep quality was significantly higher in MHD patients compared with predialysis CKD (59.5% vs 43.6%; p=0.008). Factors associated with poor sleep quality were CKD stage (p=0.035), anaemia (p=0.003), pruritus (p=0.045), anxiety symptoms (p≤0.001), depressive symptoms (p≤0.001) and reduced QoL (p≤0.001). On multivariate analysis, factors associated with poor sleep were anxiety (AOR 2.19; 95% CI 1.27 to 3.79; p=0.005), anaemia (AOR 5.49; 95% CI 1.43 to 21.00;p=0.013) and reduced physical component of QoL (AOR 4.11; 95% CI 1.61 to 10.47; p=0.003).
Conclusion: Poor sleep quality is common among patients with CKD especially in the advanced stage. The significant factors associated with poor sleep quality were QoL, anaemia and anxiety symptoms. These factors should be adequately managed to improve the overall outcomes of patients with CKD.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE