An 18-month meditation training selectively improves psychological well-being in older adults: A secondary analysis of a randomised controlled trial.

Autor: Schlosser M; Division of Psychiatry, Faculty of Brain Sciences, University College London, London, United Kingdom.; Department of Psychology, Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland., Klimecki OM; Swiss Center for Affective Sciences, University of Geneva, Geneva, Switzerland.; Clinical Psychology and Behavioral Neuroscience, Faculty of Psychology, Technische Universität Dresden, Dresden, Germany., Collette F; GIGA-CRC In Vivo Imaging, University of Liège, Liège, Belgium.; Psychology and Neuroscience of Cognition Research Unit, Faculty of Psychology and Educational Sciences, University of Liège, Liège, Belgium., Gonneaud J; Normandie Univ, UNICAEN, INSERM, U1237, PhIND 'Physiopathology and Imaging of Neurological Disorders', Neuropresage Team, Cyceron, Caen, France., Kliegel M; Department of Psychology, Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland., Marchant NL; Division of Psychiatry, Faculty of Brain Sciences, University College London, London, United Kingdom., Chételat G; Normandie Univ, UNICAEN, INSERM, U1237, PhIND 'Physiopathology and Imaging of Neurological Disorders', Neuropresage Team, Cyceron, Caen, France., Lutz A; Eduwell Team, Lyon Neuroscience Research Center Inserm U1028, CNRS UMR5292, Lyon 1 University, Lyon, France.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2023 Dec 01; Vol. 18 (12), pp. e0294753. Date of Electronic Publication: 2023 Dec 01 (Print Publication: 2023).
DOI: 10.1371/journal.pone.0294753
Abstrakt: Objectives: As the world population is ageing, it is vital to understand how older adults can maintain and deepen their psychological well-being as they are confronted with the unique challenges of ageing in a complex world. Theoretical work has highlighted the promising role of intentional mental training such as meditation practice for enhancing human flourishing. However, meditation-based randomised controlled trials in older adults are lacking. We aimed to investigate the effects of meditation training on psychological well-being in older adults.
Methods: This study presents a secondary analysis of the Age-Well trial (ClinicalTrials.gov: NCT02977819), which randomised 137 healthy older adults (age range: 65 to 84 years) to an 18-month meditation training, an active comparator (English language training), or a passive control. Well-being was measured at baseline, mid-intervention, and 18-month post-randomisation using the Psychological Well-being Scale (PWBS), the World Health Organisation's Quality of Life (QoL) Assessment psychological subscale, and composite scores reflecting the meditation-based well-being dimensions of awareness, connection, insight, and a global score comprising the average of these meditation-based dimensions.
Results: The 18-month meditation training was superior to English training on changes in the global score (0.54 [95% CI: 0.26, 0.82], p = 0.0002) and the subscales of awareness, connection, insight, and superior to no-intervention only on changes in the global score (0.54 [95% CI: 0.26, 0.82], p = 0.0002) and awareness. Between-group differences in psychological QoL in favour of meditation did not remain significant after adjusting for multiple comparisons. There were no between-group differences in PWBS total score. Within the meditation group, psychological QoL, awareness, insight, and the global score increased significantly from baseline to 18-month post-randomisation.
Conclusion: The longest randomised meditation training conducted to date enhanced a global composite score reflecting the meditation-based well-being dimensions of awareness, connection, and insight in older adults. Future research is needed to delineate the cognitive, affective, and behavioural factors that predict responsiveness to meditation and thus help refine the development of tailored meditation training.
Competing Interests: GC, FC, OMK, AL, and NLM have received research support from the EU’s Horizon 2020 research and innovation programme (grant agreement number 667696). GC has received research support from Inserm, Fondation d’entreprise MMA des Entrepreneurs du Futur, Fondation Alzheimer, Programme Hospitalier de Recherche Clinique, Région Normandie, Association France Alzheimer et maladies apparentées and Fondation Vaincre Alzheimer (all to Inserm), GC and AL have received research support and personal fees from Fondation d’entreprise MMA des Entrepreneurs du Futur. All other authors have declared that no competing interests exist. The data underlying this report are made available on request following approval by the executive committee and a formal data sharing agreement (https://silversantestudy.eu/2020/09/25/data-sharing). The Material can be mobilized, under the conditions and modalities defined in the Medit-Ageing Charter by any research team belonging to an Academic institution, for carrying out a scientific research project relating to the scientific theme of mental health and well-being in older people. The Material may also be mobilized by non-academic third parties, under conditions, in particular financial, which will be established by separate agreement between Inserm and by the said third party. Data sharing policies described in the Medit-Ageing charter are in compliance with our ethics approval and guidelines from our funding body. Data contain potentially identifying or sensitive patient information. To request data, please contact the data access committee via the official project website (https://silversantestudy.eu/2020/09/25/data-sharing). This does not alter our adherence to PLOS ONE policies on sharing data and materials.
(Copyright: © 2023 Schlosser et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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