| Autor: |
Bhat SA; Bioorganic Chemistry Division, Indian Institute of Integrative Medicine (CSIR), Srinagar, Jammu & Kashmir 190005, India. kabhat@iiim.res.in.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Ahmed QN; Natural Product and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Jammu 180001, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Bhat KA; Bioorganic Chemistry Division, Indian Institute of Integrative Medicine (CSIR), Srinagar, Jammu & Kashmir 190005, India. kabhat@iiim.res.in.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. |
| Abstrakt: |
An efficient strategy towards stereoselective amidation of alkynes is reported. The given method features operational simplicity, excellent functional group tolerance, broad substrate scope and fast kinetics to furnish Z -enamides. Moreover, the method was successfully applied for the facile synthesis of the natural products lansiumamide A, lansiumamide B and Z -alatamide. Notably, DMSO plays two vital roles: hydrogen source and solvent. |
