Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum.

Autor: Aryanian Z; Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran Iran.; Department of Dermatology Babol University of Medical Sciences Babol Iran.; Department of Dermatology School of Medicine Razi Hospital, Tehran University of Medical Sciences Tehran Iran., Balighi K; Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran Iran.; Department of Dermatology School of Medicine Razi Hospital, Tehran University of Medical Sciences Tehran Iran., Mohaghegh F; Department of Dermatology, Skin Diseases and Leishmaniasis Research Center Isfahan University of Medical Sciences Isfahan Iran., Etesami I; Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran Iran.; Department of Dermatology School of Medicine Razi Hospital, Tehran University of Medical Sciences Tehran Iran., Razavi Z; Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran Iran.; Department of Dermatology School of Medicine Razi Hospital, Tehran University of Medical Sciences Tehran Iran., Hatami P; Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran Iran.
Jazyk: angličtina
Zdroj: Clinical case reports [Clin Case Rep] 2023 Nov 27; Vol. 11 (12), pp. e8268. Date of Electronic Publication: 2023 Nov 27 (Print Publication: 2023).
DOI: 10.1002/ccr3.8268
Abstrakt: Key Clinical Message: There is a need to pay more attention to cutaneous leishmaniasis in endemic regions which may mimic other dermatoses and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR confirmation to avoid disfigurement or development of secondary malignancy.
Abstract: Leishmaniasis is a vector-borne disease with a variety of Clinical manifestations. Cutaneous leishmaniasis (CL) is the most common form of disease and can mimic other dermatoses. We describe two unusual cases of chronic leishmaniasis that remained undiagnosed for many years and led to superimposition of squamous cell carcinoma (SCC) on lesions of one patient. These reports showed that the leishmaniasis should be borne in mind by clinicians when encountering any infiltrated lesion in patients from endemic regions and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR confirmation to avoid disfigurement or development of secondary malignancy.
Competing Interests: The authors declare that they have no conflict of interest regarding the publication of this article.
(© 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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