Postoperative wound infection by nontuberculous mycobacteria; case series in Dhaka Medical College Hospital of Bangladesh.

Autor: Halder K; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Tanni NN; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Kabir RB; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Nesa M; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Rahman MF; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Zaman R; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Habib FB; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Tania NE; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Asaduzzaman M; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Haque A; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Chowdhury A; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Sarker A; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Akter N; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Chowdhury M; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Shahid SB; Department of Microbiology Dhaka Medical College Dhaka Bangladesh., Shamsuzzaman SM; Department of Microbiology Dhaka Medical College Dhaka Bangladesh.
Jazyk: angličtina
Zdroj: Clinical case reports [Clin Case Rep] 2023 Nov 27; Vol. 11 (12), pp. e8264. Date of Electronic Publication: 2023 Nov 27 (Print Publication: 2023).
DOI: 10.1002/ccr3.8264
Abstrakt: The incidence of nontuberculous mycobacterial (NTM) infections after operations is increasing in Bangladesh but data regarding clinical presentation, diagnosis, treatment, and prognosis after treatment are lacking. In this case series, three patients having persistent serous discharge from incision wound after operation were studied. Discharge from wounds were collected, wet film microscopy was performed for pus cells and fungus, Gram stain, Ziehl-Neelsen (ZN) stain, culture in routine culture media and Lowenstein-Jensen (LJ) media, Xene-Xpert for mycobacterium tuberculosis (MTB), polymerase chain reaction (PCR) for NTM were done. NTM-positive patients were treated initially for 6 weeks with four drugs regimen (clarithromycin 500 mg 12 hourly, ciprofloxacin 500 mg 12 hourly, linezolid 400 mg 12 hourly, and amikacin 500 mg 12 hourly), followed by 5 months with three drugs regimen (clarithromycin 500 mg 12 hourly, ciprofloxacin 500 mg 12 hourly, and linezolid 400 mg 12 hourly) as a maintenance dose. Cessation of discharge occurred within 3-4 weeks after starting treatment, and the wounds were healed.
Competing Interests: None.
(© 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje