[Inhibiting effect of hypoxia on the development of tumor-like formations in the fungus Fusarium bulbigenum var. blasticola].

Autor: Akhtiamov MG, Zhemaletdinov FG, Karimov MA
Jazyk: ruština
Zdroj: Eksperimental'naia onkologiia [Eksp Onkol] 1986; Vol. 8 (6), pp. 63-6.
Abstrakt: When cultivating Fusarium bulbigenum var. blasticola on the synthetic Rider media on the primary colonies tumour-like formations appear which are autonomous nondifferentiated cells. They display the resemblance with the real tumours in the following signs: differentiation, polymorphism, unlimited self-maintainance, aerobic glycolysis, etc. It is shown that under conditions of hypoxia, corresponding to the altitude of 2000-1000 m above sea-level the frequency of tumour-like formations decreases by 9-66% as compared to the cultivation conditions at pO2 of atmospheric air.
Databáze: MEDLINE